| 胎儿脑动脉分叉部中层平滑肌细胞的结构特点 |
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| 引用本文： | 赵刚,李铁林,段传志,李进.胎儿脑动脉分叉部中层平滑肌细胞的结构特点[J].南方医科大学学报,2002,22(3):267-268，274. |
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| 作者姓名： | 赵刚 李铁林 段传志 李进 |
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| 作者单位： | 1. 第一军医大学珠江医院神经外科,广东广州,510282
2. 第一军医大学组胚教研室,广东广州,510515 |
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| 摘 要： | 目的探讨人类胚胎脑动脉分叉部中层平滑肌细胞(smoothmusclecell,SMC)的构筑发育过程及特点。方法收集12~28周人类胚胎共17例,胎龄各相差1周,男女不限。对不同胎龄胚胎Willis环周围的脑动脉分叉部行三维组织切片,观察中层SMC的构筑发育过程及其有无先天缺陷。结果胎儿Willis环周各脑动脉中层SMC在1.1~9.0层之间;70.6%的胎儿在脑动脉个别分叉部发现中层SMC缺陷;所取标本的30.3%发现中层SMC缺陷。结论胎儿脑动脉中层SMC随胎龄增长而增多,但28周内不超过9.0层;本研究发现胎儿脑动脉分叉部存在先天性SMC缺陷,这将有助于对脑动脉瘤病因假说的理解和验证。
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| 关 键 词： | 血管发生 脑动脉 平滑肌 组织学 |
| 文章编号： | 1000-2588(2002)03-0267-02 |
| 修稿时间： | 2001年8月24日 |
Structural features of the smooth muscle cells in the medial layer of the bifurcation of fetal cerebral arteries |
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| ZHAOGang ,LI Tie-lin ,DUANChuang-zhi ,LI Jin.Structural features of the smooth muscle cells in the medial layer of the bifurcation of fetal cerebral arteries[J].Journal of Southern Medical University,2002,22(3):267-268，274. |
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| Authors: | ZHAOGang LI Tie-lin DUANChuang-zhi LI Jin |
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| Affiliation: | ZHAOGang 1,LI Tie-lin 1,DUANChuang-zhi 1,LI Jin 2 1 Departmentof Neurosurgery,ZhujiangHospital,FirstMilitaryMedicalUniversity,Guangzhou510282,China,2 Departmentof HistologyandEmbryology,FirstMilitaryMedicalUniversity |
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| Abstract: | Objective To studythestructuralandhistogeneticfeaturesof thesmoothmusclecells(SMCs)in themediallayer of thebifurcationof humancerebralarteriesin fetus.Method Segmentsof thecerebralarteriesfromthecircleof Willis includingthe bifurcationsof normalhumanfetusesweresectionedin1of the3orthogonalplanes,whereinthe three-dimensionalmediallayerstructurecomposedof SMCswasobservedwithlightmicroscope.Result Microscopicobservation identified1.1to9.0SMClayersinthemediallayerof thecerebralarteriesfromthecircleof Willisin thefetusesat different weeksbeforebirth,and30.3%of thespecimenswerefoundto havefocaldefectsof themedialSMClayersat thebifurcation of thedevelopingarteries.Conclusion The numberof SMC layersconsistedin themediallayersof thecerebralarteries developswiththe fetalgrowth,and the identificationof congenitalanomalyof the medialSMCs may helpverifythe hypotheticalpathogenesisforcerebralsaccularaneurysms. |
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| Keywords: | angiogenesis cerebralarteries smoothmuscles histology |
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