3-十六烷氧基-2-羟基丙基三甲基氯化铵的合成及性质研究

以十六醇、环氧氯丙烷(EPIC)与三甲胺盐酸盐合成了阳离子表面活性剂3-十六烷氧基-2-羟基丙基三甲基氯化铵(HPAC)。中间体十六烷基缩水甘油醚最佳合成条件:n(十六醇)∶n(EPIC)=1∶1.8,反应时间4 h,温度50℃,NaOH的浓度为50%,四丁基溴化铵作催化剂;HPAC最佳合成条件:n(十六烷氧基缩水甘油醚)∶n(三甲胺盐酸盐)=1∶1,温度30℃,反应3 h,HPAC的收率可达96%。研究了其界面、抗菌、抑菌性质。

Study on the synthesis and performance of 3-hexadecoxyl-2-hydroxypropyl trimethyl ammonium chloride

This paper takes epichlorohydrine(EPIC) and the hexadecyl alcohol as raw material,synthesized the active intermediate hexadecyl glycidol ether;then responses with trimethylamine muriate,producting high-quality mellow positive ion glycerine ether surface active agent 3-hexadecoxyl-2-hydroxyl propyl trimethyl ammonium chloride(HPAC).The most superior synthetic condition of hexadecyl glycidol ether:n(hexadecyl alcohol) ∶n(EPIC)=1 ∶1.8,the reaction time is 4 h,temperature is 50 ℃,the alkali concentration is 50%,four butyl ammonium bromide as the catalyst.The most superior synthetic technological condition of HPAC:n(hexadecyl oxygen radical glycidol ether) ∶n(trimethylamine muriate)=1 ∶1,the reaction temperature is 30 ℃,the reaction time is 3 h,the yield of HPAC is 96%.Studied the interface and antibactetial character of HPAC.