主动脉瓣反流容积定量的实时三维彩色多普勒血流显像研究

目的:评价实时三维彩色多普勒血流显像(RT-3D CDFI)技术无创性定量主动脉瓣反流束容积(re-gurgitant jet volume,RJV)和反流束分数(RJF%)的价值。方法:31例单纯性主动脉瓣反流患者,应用实时三维超声心动图技术采集左室的全容积数据库和三维彩色主动脉瓣反流束信号数据库,利用TomTec三维图像处理工作站分别测量左室舒张末期容积(LVEDV)、左室收缩末期容积(LVESV)和RJV,计算出RJF%。在二维超声心动图上用脉冲多普勒(PD-2D)测量计算反流容积(RV)和反流分数(RF%)。对RT-3D CDFI和PD-2D的测量值进行相关分析。结果:RT-3D CDFI和PD-2D两种方法评价主动脉瓣反流的测值相关性良好,其中RT-3DCDFI测得的RJV%与PD-2D测得的RV相关性为r=0·91,Y=0·87X 6·29,P<0·01;RT-3D CDFI测得RJF%与PD-2D测得的RF%的相关性为r=0·88,Y=0·73X 12·33,P<0·01。结论:RT-3D CDFI可从三维空间对主动脉瓣反流进行评价,为临床定量评估主动脉瓣反流提供了一种新的无创技术。

Quantitative assessment of aortic regurgitant valume with real-time three-dimensional color doppler flow imaging

Objective:To evaluate the use of the RT-3D CDFI method in the noninvasive assessment of aortic regurgitant jet volume (RJV) and regurgitant jet fraction (RJF) in patients with isolated aortic regurgitation.Method:In 31 patients with isolated aortic regurgitation, real-time three-dimensional echocardiography studies were performed to obtain LV end-diastolic volumes (LVEDV), end-systolic volumes (LVESV), and RJV, then RJF could be calculated. The regurgitant volume (RV) and regurgitant fraction (RF) calculated by two dimensional pulsed Doppler (2D-PD) method were served as reference values. Result:Aortic RJV measured by the RT- 3D CDFI method showed a good correlation with the 2D-PD measurements (r=0.91,Y=0.87X 6.29,P<0.01). %RJF estimated by the RT-3D CDFI method also correlated well with the values obtained by the 2D-PD method (r=0.88, Y=0.73X 12.33,P<0.01). Conclusion:The RT-3D CDFI method calculated regurgitant jet volume and fraction by depicting the full extent of the jet trajectory. It provides a new technique to quantitatively evaluate the valve regurgitant valume.