| 慢性乙肝患者血清转氨酶变化与肝组织学炎症程度相关性的研究 |
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| 引用本文： | 金福顺,吴晓鹭,刘家俊,陈君颖,洪延山.慢性乙肝患者血清转氨酶变化与肝组织学炎症程度相关性的研究[J].福建医药杂志,2005,27(6):139-141. |
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| 作者姓名： | 金福顺 吴晓鹭 刘家俊 陈君颖 洪延山 |
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| 作者单位： | 1. 厦门市中医院检验科,361001
2. 厦门市中医院肝科,361001 |
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| 摘 要： | 目的探讨慢性乙肝患者肝功能变化与肝组织学炎症活动程度分级（G）的相关性及临床价值。方法对60例生化指标（AST、ALT）明显异常的慢性活动性乙肝患者进行肝组织活检，观察肝组织炎症程度与肝功能生化指标的相关性。结果在所观察60例慢性乙肝患者肝功能血清生化指标异常时，肝组织均有不同程度的炎症（G），但所检测的AST、ALT并不随着炎症的增加而升高（P〉0．05）。结论肝功能血清生化指标能提示慢性乙肝患者肝组织有不同程度的炎症，但肝组织炎症程度与ALT和AST的异常程度不相关。
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| 关 键 词： | 乙型肝炎 炎症 肝组织学 血清生化指标 |
| 文章编号： | 1002-2600（2005）06-0139-03 |
Analysis of correlation of changes in serological biochemical markers to pathology in patients with chronic hepatitis B |
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| Jin Fushun , Wu Xiaolu, Liu Jiajun,et al..Analysis of correlation of changes in serological biochemical markers to pathology in patients with chronic hepatitis B[J].Fujian Medical Journal,2005,27(6):139-141. |
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| Authors: | Jin Fushun Wu Xiaolu Liu Jiajun |
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| Affiliation: | Department of Laboratory, Xiamen Hospital of Traditional Chinese Medicine, Xiamen 361001, China |
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| Abstract: | Objective To investigate the correlation of changes in serological biochemical markers to pathology(G)in patients with chronic hepatitis B(CHB)and explore its clinical significance.Methods The value of serological biochemical markers(ALT,AST)with the liver biopsy in 60 patients with CHB were analyzed.Their correlation to degrees of liver inflammation was determined.Results There were different degrees of liver inflammation when the value of the serological biochemical determined at different phases did not increase along with the degrees of liver inflammation(P>0.05).Conclusion The determination of serological biochemical markers in CHB indicates that the liver tissue has different degrees of inflammation.However,the level of abnormality of the markers is not correlated to degrees of liver tissue inflammation. |
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| Keywords: | Inflammation Chronic hepatitis B Serological biochemical markers |
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