Abstract: | Objective To study the expression of CRP, IL-6 and TNF-a in the serum of patients with the suspected adolescence polycystic ovary syndrome (PCOS). Methods 80 patients with the suspected adolescence polycystic ovary syndrome (PCOS)were selected as the object of study (suspected adolescence PCOS group), and 60 patients with adolescence PCOS were chosen as the PCOS group and60 normal adolescence women selected as the control group. The 80 subjects were divided into two subgroups: OA+PCOM group (40 cases) and OA+HA group (40 cases). The levels of FSH, LH, T, E2, PRL, CRP, IL-6, TNF-a were detected. Results Serum levels of CRP、IL-6 in suspected adolescence PCOS group were significantly higher than those in the control group (P < 0.05). Serum levels of CRP, TNF-a and IL-6 in OA+HA group were significantly higher than those in OA+PCOM group (P < 0.05). Conclusion The high levels of IL-6 and CRP in patients with the suspected adolescence PCOS may help to identify the early puberty and provide the evidence for the early intervention of adolescence PCOS. |