妊娠期肝内胆汁淤积症67例临床分析

目的 探讨妊娠期肝内胆汁淤积症(ICP)的危害、监护与诊治方法.方法 以67例ICP患者为研究对象,并选择同期分娩的70例非ICP患者作为对照组,进行回顾性分析.结果 研究组胎儿窘迫率、羊水污染率、早产率、剖宫产率及产后出血率均显著高于对照组,差异有显著性(P＜0.05).结论 ICP对胎儿危害严重,及时诊断、积极治疗、密切胎儿监护并适时终止妊娠能有效改善妊娠结局.

Clinical study on 67 cases of intrahepatic cholestasis during pregnancy

Objective To explore the hazard of intrahepatic cholestasis during pregnancy （ICP） and the method for its monitoring, diagnosis and treatment. Methods The clinical data of 67 cases of ICP were retrospectively analyzed, and 70 normal pregnant women were selected as control group. Results In comparison with control group, there were significant differences in rates of contaminated amniotic fluid, fetal distress, preterm labor, cesarean section and postpartum hemorrhage （ P 〈 0.05 ）. Conclusion ICP will cause serious hazard to embryo, hence prompt diagnosis, proper treatment, carefully monitoring and timely termination of pregnancy are effective ways to improve the outcome of pregnancy.