人类辅助生殖技术研究进展

自从世界上第1例"试管婴儿"诞生以来,人类辅助生殖技术已经走过了30年的发展历程。随着人们对配子与胚胎培养条件的不断优化,辅助生殖技术的成功率显著提高,现已成为治疗不孕不育症的理想治疗措施之一。近年来,一系列辅助生殖相关技术,如卵子体外成熟、移植前遗传学诊断、单胚胎移植以及冷冻技术等获得了较大的发展,为降低常规体外受精—胚胎移植的费用、风险等提供了可能。该文主要就当前临床及实验性辅助生殖技术的相关研究进展作以综述。

Progress in research on human assisted reproductive technology

Since birth of the world's first "test-tube baby",human assisted reproductive technology(ART) has experienced 30-year development.The success rate of ART has been improved significantly along with continuous optimalization in culture conditions of gametes and embryos.ART has become one of optimal treatments of infertility.In recent years,a series of related assisted reproductive technologies such as in vitro oocyte maturation(IVM),preimplantation genetic diagnosis(PGD),single embryo transfer and gamete and embyo freezing and frost thawing technology have been developed,which provides possibilities to reduce cost and risk of routine in vitro fertilization and embryo transfer(IVF-ET).This paper viewed progress in clinical and experimental researches on ART.