活血化瘀方药对突发性耳聋患者BAEP及TCD脑血流参数的影响

目的观察血府逐瘀汤方药治疗突发性耳聋（简称突聋）患者的效果。方法选取60例突聋患者给予血府逐瘀汤，分别检测治疗前后的脑干听觉诱发电位（BAEP）、经颅多普勒（TCD）脑血流参数，并进行统计学分析。结果突聋患者BAEP的Ⅰ、Ⅲ、Ⅴ波波形及峰潜伏期（PL），椎基底动脉血流速度及脑血流参数的不同程度地改善。结论活血化瘀方药可改善突聋患者BAEP及TCD脑血流参数，进行BAEP、TCD检测可反映突聋患者内耳及脑干的神经功能和供血状况，对指导临床治疗及评价预后有重要意义。

Effect of TCM Formula for Promoting Blood Circulation to Remove Blood Stasis on Brainstem Auditory Evoked Potential and Transcranial Doppler Parameters in Patients with Sudden Deafness

OBJECTIVE: To observe the therapeutic effect of Xuefu Zhuyu Decoction (XZD) on patients with sudden deafness (SD). METHODS: Sixty patients with SD were treated with XZD, and the changes of brainstem auditory evoked potential (BAEP) and transcranial Doppler (TCD) parameters in them were detected before and after treatment and analyzed statistically. RESULTS: I, III and V waveform and peak latency (PL) of BAEP, velocity of vertebral basilar arterial blood flow and parameters of cerebral blood flow in SD patients were all improved to different levels after treatment with XZD. CONCLUSION: TCM formula for promoting blood circulation to remove blood stasis can improve BAEP and TCD parameters in SD patients; BAEP detection and TCD parameters can reflect nerve function and blood-supply state of internal ear and brain stem, and therefore are of great importance in guiding the clinical treatment and assessing the prognosis.