| 心脏房间隔缺损/卵圆孔未闭封堵器——从不降解到可降解 |
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| 引用本文： | 王一涵,窦红静,孙康,李奋,戴柯,孙锟. 心脏房间隔缺损/卵圆孔未闭封堵器——从不降解到可降解[J]. 材料导报, 2009, 23(19) |
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| 作者姓名： | 王一涵 窦红静 孙康 李奋 戴柯 孙锟 |
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| 作者单位： | 1. 上海交通大学金属基复合材料国家重点实验室,上海,200240
2. 上海市儿童医学中心,上海,200127 |
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| 基金项目： | 国家自然科学基金，上海市科委优秀学科带头人计划，申康市级医院新兴前沿技术联合攻关项目 |
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| 摘 要： | 房间隔缺损和卵固孔未闭是临床常见的2种先天性心脏发育畸形.封堵器作为介入治疗房间隔缺损和卵圆孔未闭的装置,其作用是对房间隔上面未能闭合的孔进行封闭.可调节与可吸收是新型封堵器的2个发展方向.介绍了国内外封堵器装置的种类、特点以及临床实验情况,结合现有一些生物可降解的高分子材料,分析了可生物吸收、可生物降解封堵器的研究意义和可行性.
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| 关 键 词： | 房间隔缺损 卵圆孔未闭 封堵器 可降解 高分子纤维 |
ASD/PFO Devices:from Non-degradable to Degradable |
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| WANG Yihan,DOU Hongjing,SUN Kang,LI Fen,DAI Ke,SUN Kun. ASD/PFO Devices:from Non-degradable to Degradable[J]. Materials Review, 2009, 23(19) |
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| Authors: | WANG Yihan DOU Hongjing SUN Kang LI Fen DAI Ke SUN Kun |
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| Abstract: | Atrial septal defect (ASD) and patent foramen ovale (PFO) are two common types of congenital heart malformations. Occluder, as transcatheter closure device, has been designed to close congenital heart defects. Various types of occluder are currently available commercially or within clinical trials. Adjustable and biodegradable are two development directions of occluder. Several types of occluder at home and abroad, including their shapes, characteristics, as well as clinical trials are introduced. In combin... |
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| Keywords: | ASD PFO occluder degradable polymer fiber |
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