| 肉苁蓉抗氧化作用及对超氧化物歧化酶活性的影响 |
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| 引用本文： | 谢继红,吴春福,邹宇宏,刘雯,高集馥.肉苁蓉抗氧化作用及对超氧化物歧化酶活性的影响[J].中药药理与临床,1993(4). |
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| 作者姓名： | 谢继红 吴春福 邹宇宏 刘雯 高集馥 |
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| 作者单位： | 大连医药科学研究所 116013
(谢继红)，沈阳药学院中药药理教研室 110015
(吴春福，邹宇宏，刘雯)，大连医药科学研究所 116013(高集馥) |
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| 摘 要： | 肉苁蓉乙醇提取物在体外温育体系中能显著抑制大鼠脑、肝、心、肾、睾丸组织匀浆过氧化脂质的生成,并呈现良好的量效关系。体内实验中,该提取物100、200mg/kg/日,连续灌胃40天,仅对大鼠大脑皮层过氧化脂质生成有显著抑制作用,对其它组织无明显影响,200mg/kg/日灌胃15天,对大鼠血浆超氧化物歧化酶活性有显著增强作用。
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| 关 键 词： | 肉苁蓉 抗脂质过氧化 超氧化物歧化酶 |
Effect of Cistanche deserlicola on Lipid Peroxidation and Superoxide Dismutase in Rat |
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| Xie Jihong,Wu Chunfu.Effect of Cistanche deserlicola on Lipid Peroxidation and Superoxide Dismutase in Rat[J].Pharmacology and Clinics of Chinese Materia Medica,1993(4). |
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| Authors: | Xie Jihong Wu Chunfu |
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| Affiliation: | Xie Jihong*,Wu Chunfu, |
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| Abstract: | The ethanolic extract of C. deserlicola, in vitro, could significantly inhibit the lipid peroxidation in the homogenates of rat brain, liver, heart, kedney and testis in dose-dependent manner from 0.0625 to 6.2500mg/ml. However, in vivo experiment showed that the extract 100, 200mg/kg/day po. for 40 days inhibited the lipid peroxid-ation only in rat brain, but not in other tissues. At the dose of 200mg/kg po. for 15 days the extract increased the activity of superoxide dismutase in rat plasma. |
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| Keywords: | Cistanche deserlicola Anti-peroxidation Superoxide dismutase |
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