| 奥硝唑口腔膜剂的制备及质量控制 |
| |
| 引用本文： | 安媛,孙德江.奥硝唑口腔膜剂的制备及质量控制[J].中国药房,2005,16(12):908-909. |
| |
| 作者姓名： | 安媛 孙德江 |
| |
| 作者单位： | 1. 山东烟台市莱阳中心医院,莱阳市,265200
2. 山东莱阳卫生学校,莱阳市,265200 |
| |
| 摘 要： | 目的:制备奥硝唑口腔膜剂并建立其质量控制方法。方法:以聚乙烯醇、羧甲基纤维素钠等为辅料制备奥硝唑口腔膜剂;采用紫外分光光度法测定其主药奥硝唑含量,测定波长为316nm。结果:奥硝唑检测浓度在6.0～18.0μg/ml范围内线性关系良好(r=0.9997),平均回收率为100.19%(RSD=0.66%,n=5)。结论:该膜剂制备工艺简单,含量测定快速、准确,质量可控。
|
| 关 键 词： | 奥硝唑 口腔膜剂 质量控制 |
| 文章编号： | 1001-0408(2005)12-0908-02 |
| 修稿时间： | 2004年11月2日 |
Preparation and Quality Control of Ornidazole Stomatic Membrane |
| |
| AN Yuan,SUN Dejiang.Preparation and Quality Control of Ornidazole Stomatic Membrane[J].China Pharmacy,2005,16(12):908-909. |
| |
| Authors: | AN Yuan SUN Dejiang |
| |
| Abstract: | OBJECTIVE:To investigate the method for preparation and quality control of ornidazole oral membrane.METHODS:Ornidazole oral membrane was prepared with polyvinyl alcohol and sodium carboxymethylcellulose as its adju-vants;The content of ornidazole was determined by ultraviolet spectrophotometry at the wavelength of316nm.RESULTS:There was a good linear correlation within a range of6.0～18.0μg/ml(r=0.9997)of ornidazole concentration,the average recovery was100.19%(RSD=0.66%,n=5).CONCLUSION:The established technique is simple,and the content deter-mination is quick,precise and reliable. |
| |
| Keywords: | Ornidazole Oral membrane Quality control |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
