| 盐酸丁丙诺啡片治疗海洛因依赖者临床观察 |
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| 引用本文： | 罗晓云,杨介文,张子辰,牛冠英,刘志民,陆明,蔡志基.盐酸丁丙诺啡片治疗海洛因依赖者临床观察[J].中国药物依赖性杂志,1994(3). |
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| 作者姓名： | 罗晓云 杨介文 张子辰 牛冠英 刘志民 陆明 蔡志基 |
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| 作者单位： | 广州江村自愿戒毒所，广州江村自愿戒毒所，广州江村自愿戒毒所，广州江村自愿戒毒所，北京医科大学中国药物依赖性研究所，北京医科大学中国药物依赖性研究所，北京医科大学中国药物依赖性研究所 广州，510450，广州，510450，广州，510450，广州，510450，北京，100083，北京，100083，北京，100083 |
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| 摘 要： | 本文报告81例海洛因依赖者单用盐酸丁丙诺啡片,采用递减法戒毒的临床效果。结果表明,60例完成治疗过程,效果良好;21例脱试。平均住院7.3d,盐酸丁丙诺啡片人均用量27.1mg;含服后1h作用达高峰,维持6-8h。7d内快速递减后,戒断症状控制好,副作用小,使用方便,自身成瘾性潜力低,不失为戒毒良药。
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| 关 键 词： | 盐酸丁丙诺啡 海洛因依赖 戒断症状 戒毒 |
CLINICAL STUDY ON THE TREATMENT OF HEROIN ADDICTS BY BUPRENORPHINE HYDROCHLORIDE TABLETS |
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| LUO Xiao-Yun,YANG Jie-Wen,ZHANG Zi-Chen,NIU Guan - Ying,LIU Zhi - Min,LU Ming,CAI Zhi - Ji.CLINICAL STUDY ON THE TREATMENT OF HEROIN ADDICTS BY BUPRENORPHINE HYDROCHLORIDE TABLETS[J].Chinese Journal of Drug Dependence,1994(3). |
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| Authors: | LUO Xiao-Yun YANG Jie-Wen ZHANG Zi-Chen NIU Guan - Ying LIU Zhi - Min LU Ming CAI Zhi - Ji |
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| Abstract: | 81 cases of heroin addicts were treated only by buprenorphine hydrochlo-ride tablets(Bup)with the dosage decreasing gradually.The results were that 60 cases were detoxified; 21 cases dropped out during the test.The effective rate was 74 %.The mean duration of the addicts in hospital was 7.2 days; the mean dosage of Bup used per person was 27.1 mg.The efective peak appeared 1 hour later after Bup wsa taken and maintained 6-8 hours.By decreasing the doses of Bup quickly within 7 days,the abstinence syndromes were effectively controlled.The drug's adverse reaction and dependence potential were low.It was convenient to use.Therefore,Bup might be a good medicine for heroin detoxification. |
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| Keywords: | buprenorphine hydrochloride heroin dependence abstinence syndrome detoxification |
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