|
|||||
|
|
| 高压液相色谱法测定兔缺血再灌注肝脏ATP含量 | |
| 引用本文： | 李晓晔,柳巍,吴红,许兵,宋振顺,许自超.高压液相色谱法测定兔缺血再灌注肝脏ATP含量[J].现代科学仪器,2000(2):28-29. |
| 作者姓名： | 李晓晔 柳巍 吴红 许兵 宋振顺 许自超 |
| 作者单位： | 1. 第四军医大学化学教研室,西安,710032 2. 上海师范大学化学系 3. 第四军医大学西京医院普通外科 |
| 摘 要： | 用高压液相色谱法测定了肝脏缺血再灌注后ＡＴＰ含量的变化。应用预防损伤的药物氯丙嗪和异博定后，兔肝组织ＡＴＰ含量明显高于不用药的对照组，说明钙离子拮剂有预防缺血再灌注损伤的作用，其作用机理与减少钙离子内流，维持和促进一代谢的正常有关。 |
| 关 键 词： | 高压液相色谱 再灌注 肝脏缺血 ATP含量 兔 测定 |
Determination of ATP in the rabbits liver with ischemia reperfused by HPLC |
|
| Li Xiaoye,Liu Wei,Wu Hong,Xu Bing,Song Zhenshun,Xu Zichao.Determination of ATP in the rabbits liver with ischemia reperfused by HPLC[J].Modern Scientific Instruments,2000(2):28-29. | |
| Authors: | Li Xiaoye Liu Wei Wu Hong Xu Bing Song Zhenshun Xu Zichao |
| Abstract: | The change alteration of ATP after liver ischemia reperfused was Investigated using HPLC,After Chlorpromazinum and isoptin were used, the content of ATP in the rabbits liver is significantly higher than the contrast group without drugs. Calcium antagonists can prevent injury from ischemia reperfused, The function mechanism could be concerned in reducing calcium ion from outer_cell into inner_cell, maintaining and promoting the balance of the cell energy metabolism. |
| Keywords: | HPLC Ischemia reperfused Liver ATP |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |
