| 伽玛刀治疗三叉神经痛照射剂量研究 |
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| 引用本文： | 王宏伟,窦长武,张国荣,何占彪.伽玛刀治疗三叉神经痛照射剂量研究[J].立体定向和功能性神经外科杂志,2011(3):169-172. |
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| 作者姓名： | 王宏伟 窦长武 张国荣 何占彪 |
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| 作者单位： | 内蒙古医学院附属医院头部伽玛刀治疗中心; |
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| 基金项目： | 内蒙古自治区教育厅基金项目(编号:NJZY07094) |
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| 摘 要： | 目的 ;研究伽玛刀治疗原发性三叉神经痛的最佳照射剂量。方法选择2004年1月~2010年3月期间经保守治疗无效的原发性三叉神经痛患者进行伽玛刀治疗。根据不同的照射剂量随机分为高剂量组(80~85Gy)和低剂量组(70~75 Gy),治疗后定期随访,进行疗效分析。结果本组总计65例患者,随访60例,失访5例,随访率92.3%,随访期12~78个月,平均随访期36个月。对两组共60例患者进行了统计学分析,其中高剂量组25例,低剂量组35例。高剂量组1例无效,有效率96%,低剂量组2例无效,有效率94.3%,两组有效率无差异(P>0.05)。高剂量组出现面部麻木17例,并发症发生率68%,低剂量组出现面部麻木7例,并发症发生率20%,两组并发症发生率有显著差异(P<0.05)。高剂量组治疗后疼痛完全缓解时间为2.51个月,低剂量组治疗后疼痛完全缓解时间为2.67个月,两组疼痛缓解时间无差异(P>0.05)。结论伽玛刀治疗原发性三叉神经痛安全有效,70~75 Gy应作为最佳照射剂量。
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| 关 键 词： | 原发性三叉神经痛 伽玛刀 |
Study of radiation dose of gamma knife radiosurgery for primary trigeminal neuralgia |
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| Wang Hongwei,Dou Changwu,Zhang Guorong,et al..Study of radiation dose of gamma knife radiosurgery for primary trigeminal neuralgia[J].Chinese Journal of Stereotactic and Functional Neurosurgery,2011(3):169-172. |
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| Authors: | Wang Hongwei Dou Changwu Zhang Guorong |
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| Affiliation: | Wang Hongwei,Dou Changwu,Zhang Guorong,et al.Gamma Knife Center The Affiliated Hospital of Inner Mongolia Medical College,Huhhot,010050 |
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| Abstract: | Objective To Study best radiation dose of gamma knife radiosurgery for primary trigeminal neuralgia.Methods Between January 2004 and March 2010,65 patients with primary trigeminal neuralgia were treated with gamma knife radiosurgery.The patients were randomly divided into high-dose group(80-85Gy) and low-dose group(70~75Gy).After treatment,the patients were followed-up for long time.Results Total of 65 patients in the group,60 patients were followed up,lost in 5 cases,follow-up rate was 92.3%,follow-up peri... |
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| Keywords: | Trigeminal neuralgia Gamma knife |
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