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紫外分光光度法测定洁阴灵中醋酸氯已定和氧氟沙星含量
引用本文:聂小岗,罗水平,程小平.紫外分光光度法测定洁阴灵中醋酸氯已定和氧氟沙星含量[J].中国医院药学杂志,2001,21(2):87-88.
作者姓名:聂小岗  罗水平  程小平
作者单位:1. 上饶地区药品检验所,
2. 上饶新星制药有限公司,
摘    要:目的:建立洁阴灵中醋酸氯已定和氧氟沙星含量检测方法。方法:采用双波长分光光度法,在波长255,269.4nm处,测定醋酸氯已定含量,在波长326nm处,测定氧氟沙星含量,结果:醋酸氯已定平均回收率为99.6%,RSD为0.8%(n=9),氧氟沙星平均回收率为99.85,RSD为0.3%,(n=9),结论:该方法简便、准确、可用于洁阴灵中醋酸氯已定和氧氟沙星含量测定。

关 键 词:紫外分光光度法  醋酸氯已定  氧氟沙星  洁阴灵  含量
文章编号:1001-5213(2001)02-0087-02
修稿时间:2000年3月10日

Determination of chlorhexidine acetate and ofloxacin in Jie yin ling by ultraviolet spectrophotometry
NIE Xiao-Gang,LUO Shui-Ping,CHENG Xiao-ping.Determination of chlorhexidine acetate and ofloxacin in Jie yin ling by ultraviolet spectrophotometry[J].Chinese Journal of Hospital Pharmacy,2001,21(2):87-88.
Authors:NIE Xiao-Gang  LUO Shui-Ping  CHENG Xiao-ping
Affiliation:NIE Xiao-Gang 1,LUO Shui-Ping 1,CHENG Xiao-Ping 2
Abstract:OBJECTIVE:To establish a method for determination of chlorhexidine acetate and ofloxacin in Jie yin ling.METHODS:Dual wavelength spectrophotometry was used to determine the chlorhexidine content,at 255 nm and 269.4 nm.The ofloxacin was determined by spectrophotometry,at 326 nm.RESULTS:The average recovery for chlorhexidine acetate was 99.6% ,RSD= 0.8% (n=9);and the average recovery for ofloxacin was 99.8% ,RSD= 0.3% (n=9).CONCLUSIONS:The method is simple,fast and accurate.
Keywords:ultroviolet spectrophotometry  chlorhexidine acetate  ofloxacin  
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