Platyphylloside: Metabolism and digestibility reductionin vitro |
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| Authors: | Kerstin Sunnerheim-Sjöberg Per-Göran Knutsson |
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| Affiliation: | (1) Department of Chemistry, Uppsala University, Box 531, S-751 21 Uppsala, Sweden;(2) Department of Animal Physiology, Swedish University of Agricultural Sciences, Box 7045, S-750 07 Uppsala, Sweden |
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| Abstract: | The metabolism of platyphylloside (5S)-5-hydroxy-1,7-bis-(4-hydroxyphenyl)-3-heptanone-5-O- -d-glucopyranosidel]—known to reduce digestibility—was studiedin vitro in sheep rumen liquor. Platyphylloside is hydrolyzed to 5-hydroxy-3-platyphyllone (5S)-5-hydroxy-1,7-bis-(4-hydroxyphenyl)-3-heptanone], which is reduced to centrolobol 1,7-bis-(4-hydroxyphenyl)-3-heptanol], via 3-platyphyllone 7-bis-(4-hydroxyphenyl)-3-heptanone]. The digestibility-reducing effect was shown to be correlated with the concentration of centrolobol. |
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| Keywords: | Phenols platyphylloside 5-hydroxy-3-platyphyllone 3-platyphyllone centrolobol metabolites digestibility rumen liquor birch |
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