| 朱砂根化学成分和药理作用的研究进展 |
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| 引用本文： | 叶晴,陈金鹏,凌悦,刘怡妙,刘毅,盖晓红,田成旺,陈常青.朱砂根化学成分和药理作用的研究进展[J].中草药,2022,53(9):2851-2860. |
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| 作者姓名： | 叶晴 陈金鹏 凌悦 刘怡妙 刘毅 盖晓红 田成旺 陈常青 |
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| 作者单位： | 天津中医药大学, 天津 301617;天津药物研究院, 天津 300462;天津市中药质量标志物重点实验室, 天津 300462;释药技术与药代动力学国家重点实验室, 天津 300462 |
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| 基金项目： | 国家重点研发计划项目（2018YFC1708100）；国家自然科学基金青年科学基金项目（82003936）；中医药国际合作专项（基地类项目）（0610-2140NF020630） |
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| 摘 要： | 朱砂根Ardisiae Crenatae Radix是一种民间常见的观赏性中药材，具有解毒消肿、活血止痛、祛风除湿的功效，是贵州特色民族药八爪金龙的3大来源之一。朱砂根主要含有香豆素类、皂苷类、黄酮类、挥发油等多种化学成分，具有抗炎、抗肿瘤、抗氧化、降血糖、保肝、抗生育等药理作用。主要综述了朱砂根化学成分和药理作用的研究进展，旨在为朱砂根的进一步开发和应用提供参考。
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| 关 键 词： | 朱砂根 香豆素 黄酮 皂苷 挥发油 抗炎 抗肿瘤 抗氧化 |
| 收稿时间： | 2021/9/22 0:00:00 |
Research progress on chemical constituents and pharmacological effects of Ardisiae Crenatae Radix |
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| YE Qing,CHEN Jin-peng,LING Yue,LIU Yi-miao,LIU Yi,GAI Xiao-hong,TIAN Cheng-wang,CHEN Chang-qing.Research progress on chemical constituents and pharmacological effects of Ardisiae Crenatae Radix[J].Chinese Traditional and Herbal Drugs,2022,53(9):2851-2860. |
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| Authors: | YE Qing CHEN Jin-peng LING Yue LIU Yi-miao LIU Yi GAI Xiao-hong TIAN Cheng-wang CHEN Chang-qing |
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| Affiliation: | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China;Tianjin Institute of Pharmaceutical Research, Tianjin 300462, China;Tianjin Key Laboratory of Quality Marker of Traditional Chinese Medicine, Tianjin 300462, China;State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin 300462, China |
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| Abstract: | Zhushagen (Ardisiae Crenatae Radix) is a kind of common folk ornamental Chinese medicinal material with the effects of detoxification and relieving swelling, activating blood circulation and relieving pain, expelling wind and removing dampness. It is also one of the three major sources of Ardisia crispa which was considered to a characteristic ethnic medicinal material in Guizhou. Ardisiae Crenatae Radix mainly contains coumarins, saponins, flavonoids, volatile oils and other chemical constituents, with the pharmacological effects of anti-inflammation, anti-tumor, anti-oxidation, hypoglycemic, liver protection, anti-fertility and so on. Research progress on chemical constituents and pharmacological effects of Ardisiae Crenatae Radix were mainly discussed in this paper, in order to provide reference for further development and application of Ardisiae Crenatae Radix. |
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| Keywords: | Ardisiae Crenatae Radix coumarins flavonoids saponins volatile oils anti-inflammation anticancer antioxidant |
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