武汉同济医院血液科病房近5年病原菌分布及耐药性监测

目的了解武汉同济医院血液科病房2005-2009年病原菌分布和耐药现状。方法药敏试验采用K-B法,WHONET 5.4软件进行数据分析。结果共分离病原菌667株,革兰阴性菌占54.3%,革兰阳性菌占31.5%,真菌占14.2%;标本主要来源为血液占31.9%,痰液占20.5%和尿液占11.2%,前5位细菌依次为凝固酶阴性葡萄球菌、大肠埃希菌、铜绿假单胞菌、肺炎克雷伯菌和白色假丝酵母菌,肺炎克雷伯菌及大肠埃希菌超广谱β-内酰胺酶(ESBLs)阳性率分别为48.9%和79.5%,耐甲氧西林凝固酶阴性葡萄球菌(MRCNS)和耐甲氧西林金黄色葡萄球菌(MRSA)分别占73.8%和26.4%。结论血液病房病原菌以革兰阴性杆菌为主,真菌比例上升较快;主要病原菌耐药现象较前加重。

Distribution and antibiotic resistance surveillance of pathogens isolated from hematology wards of Wuhan Tongji hospital in recent five years

OBJECTIVE To investigate the distribution and antibiotic resistance of infection pathogens isolated from hematology ward Wuhan Tongji Hospital from 2005 to 2009.METHODS Bacterial susceptibility test was carried out using K-B method.Data were analyzed by WHONET 5.4 software.RESULTS A total of 667 clinical isolates were collected,including Gram-negative bacilli(54.3%),Gram-positive cocci(31.5%) and fungi(14.2%).The dominant source of pathogens was blood(31.9%),sputum(20.5%) and urine(11.2%).The top five patho...