Physical,mechanical, and in vitro biological analysis of bioactive fibers-based dental composite |
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| Authors: | Mehvish Saleem Saba Zahid Sarah Ghafoor Hina Khalid Haffsah Iqbal Rabia Zeeshan Sarfraz Ahmad Anila Asif Abdul Samad Khan |
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| Affiliation: | 1. Department of Dental Materials, University of Health Sciences, Lahore, Pakistan;2. Interdisciplinary Research Centre in Biomedical Materials, COMSATS University Islamabad, Lahore, Pakistan;3. Department of Oral Biology, University of Health Sciences, Lahore, Pakistan;4. Department of Chemistry, University of Malaya, Kuala Lumpur, Malaysia;5. Department of Restorative Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia |
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| Abstract: | This study aimed to synthesize experimental composites reinforced with various concentrations (0, 40, 50, and 60 wt%) of nano-hydroxyapatite grafted glass fibers. The release of monomers, residual monomers, and in-vitro bioactivity of composite groups were evaluated after 1, 7, and 28 days. Compressive strength/ modulus, cell viability (by direct and indirect method), and bacterial adhesion were evaluated. The results showed that bis-GMA was released from all samples. TEGDMA released from 50 and 60 wt% samples on day 1 and UDMA showed negligible release. Compressive strength values of 40 wt% sample were higher than other experimental groups. New apatite layer was formed, whereby both direct and indirect methods demonstrated cell viability. The numbers of active colonies grown were least for 60 wt% sample while their number increased over time. The nano-hydroxyapatite/glass fibers have potential to be used as filler in dental composites and experimental composites were found to be biocompatible and comparable with commercial material. |
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| Keywords: | biocompatibility biomedical applications composites E-glass fibers mechanical properties nanohydroxyapatite spectroscopy |
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