乳果糖口服溶液治疗习惯性便秘39例疗效观察

目的观察乳果糖口服溶液治疗习惯性便秘的疗效及安全性。方法将78例患者按随机数字表法分为2组,治疗组39例,用乳果糖口服溶液10-15 mL·次^-1,晨起1次口服,疗程2周;对照组39例,用麻仁软胶囊1.2 g,口服,3次·d^-1,疗程2周。结果治疗组总有效率为97.44%,对照组总有效率为87.18%,2组比较差异有统计学意义（P〈0.05）。结论乳果糖口服溶液治疗习惯性便秘疗效确切。

Therapeutic Effects of Oral Lactulose Solution in 39 Cases of Habitual Constipation

Objective To observe the therapeutic effects and security of oral lactulose solution in treatment of habitual constipation.Methods Seventy-eight cases of habitual constipation were randomly divided into two groups in a prospective self-control way,with 39 cases in each group.The patients in therapy group were given 10-15 mL oral lactulose solution once every morning for 2 weeks.The patients in control group were given 1.2 g Maren capsules 3 times per day for 2 weeks.Results Total effective rate in therapy group and control group was 97.44% and 87.18%,respectively,and there was a significant difference between the two groups（P〈0.05）.Conclusion Oral lactulose solution is effective in treating habitual constipation.