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慢性肝病患者红细胞免疫功能的研究
引用本文:张晨光,高继君,李方都.慢性肝病患者红细胞免疫功能的研究[J].实用肝脏病杂志,2003,6(3):146-147.
作者姓名:张晨光  高继君  李方都
作者单位:233040,蚌埠铁路中心医院传染科
摘    要:目的 探讨慢性肝病患者红细胞免疫粘附功能的变化。方法 检测73例慢性乙型肝炎及肝硬化患者红细胞C_3b受体花环形成率(RBC-C_3bRR)、红细胞免疫复合物花环形成率(RBC-ICRR)及患者的循环免疫复合物(CIC)水平。结果 与正常对照组相比,RBC-C_3bRR在慢性肝炎中、重度及肝硬化患者中明显下降(P<0.01),在慢性肝炎轻度也有显著下降(P<0.05)。而RBC-ICRR在慢性肝炎中重度及肝硬化患者中明显升高(P<0.05)。各型肝病患者CIC均明显升高。结论 慢性肝炎患者的红细胞免疫粘附功能有明显改变,其意义有待进一步研究。

关 键 词:慢性肝病  红细胞免疫

Red blood cell immune functions in patients with chronic liver diseases
Zhang Chenguang,Gao Jijun,Li Fangdu.Red blood cell immune functions in patients with chronic liver diseases[J].Journal of Clinical Hepatology,2003,6(3):146-147.
Authors:Zhang Chenguang  Gao Jijun  Li Fangdu
Abstract:Objective To investigate red blood cell immune adhesive function in patients with chronic liver diseases. Methods Serum RBC-C3bRR and RBC-ICRR were detected in 73 patients with chronic hepatitis B or with liver cirrhosis. Results Serum RBCC3bRR level in moderate and severe chronic hepatitis were notably decreased. Differences were significant in comparison with that of normal control group( P<0.01 ). Mild chronic hepatitis were obviously lower than that of normal control group too( P<0.05). Serum RBCICRR in moderate,severe hepatitis and liver cirrhosis were obviously higher than that of control group (p<0.05). Conclusion The red blood cell immune function in patients with chronic liver disease decreased, which might influence clearing away CIC and leading to damage of liver cells.
Keywords:Chronic live diseases Red blood cells Immune founetion
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