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Toxoplasma prevalence among pregnant women in Norway: a cross‐sectional study
Authors:Gry Findal  Regine Barlinn  Irene Sandven  Babill Stray‐Pedersen  Svein A Nordbø  Helvi H Samdal  Kirsti Vainio  Susanne G Dudman  Pål A Jenum
Affiliation:1. Institute of Clinical Medicine, University of Oslo, Oslo, Norway;2. Division of Women and Children, Oslo University Hospital, Oslo, Norway;3. Department of Virology, Norwegian Institute of Public Health, Oslo, Norway;4. Oslo Centre for Biostatistics and Epidemiology, Research Support Services, Oslo University Hospital, Oslo, Norway;5. Department of Medical Microbiology St.Olavs Hospital, Trondheim, Norway;6. Department of Microbiology, Oslo University Hospital, Oslo, Norway;7. Department of Medical Microbiology, Vestre Viken Health Trust, Drammen, Norway
Abstract:Infection by Toxoplasma gondii may lead to complications in the foetus if the mother suffers from primary infection during pregnancy . Previously infected women have produced toxoplasma‐specific IgG antibodies. The most recent study on prevalence of toxoplasma IgG in the Norwegian pregnant population was conducted 20 years ago. The present study is part of a research programme initiated by the Norwegian Institute of Public Health. We aimed to update the knowledge regarding the prevalence of toxoplasma IgG among pregnant women in Norway. In this cross‐sectional study, sera from 1922 pregnant women in Buskerud (992) and Sør‐Trøndelag counties (930) in Norway were collected consecutively. The presence of toxoplasma IgG was identified by values ≥8 IU/mL using an ELISA test. The overall prevalence of toxoplasma IgG seropositivity was 9.3% (95% CI 8.1–10.7); Sør‐Trøndelag 10.4% (95% CI 8.6–12.6) and Buskerud 8.3% (95% CI 6.7–10.2). There was no difference between the counties (p = 0.13), and the result did not differ from prevalences found in 1974 (12.1%) and 1994 (10.7%). We found a higher prevalence among women ≥40 years (OR 2.65, 95% CI 1.30–5.42). The prevalence of toxoplasma IgG among pregnant women in Norway is low and has been stable during the last decades.
Keywords:Toxoplasma gondii  pregnancy  prevalence  IgG antibody  cross‐sectional
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