在广元市无偿献血者中开展丙氨酸氨基转移酶筛查的探讨

目的 探讨在献血者中开展丙氨酸氨基转移酶(ALT)筛查的可行性.方法 通过对2010年7月1日至9月30日5 376例无偿献血者进行ALT筛查,将其筛查结果与同时期3年内实验室无偿献血者ALT检测结果进行对比分析.结果 在无偿献血者中,再次献血不合格率(8.56%)较初次献血者(10.47%)偏低,复检不合格率(5.42%)较初筛(9.80%)偏低,差异有统计学意义(P＜0.05).通过开展献血前ALT筛查,2010年ALT不合格率较2008年和2009年低,差异有统计学意义(P＜0.01).ALT不合格主要与献血前饮酒(26.00%)、疲劳(29.60%)等相关.结论 在献血前开展ALT项目的 筛查,既保护了献血者的身体健康,也有效避免血液不必要的浪费,节约了血液资源.

Study of ALT screening of unpaid blood donation in Guangyuan city

Objective To investigate the feasibility of ALT screening in blood donation.Methods 5 376 cases in blood donation from 1st July,2010 to 30th September were carried out ALT screening,and compared the screening results with the laboratory test results of ALT in the same period of 3 years.Results The failure rate of blood redonation was lower than that in the first time blood donors.The failure rate of recheck was lower than that in ALT screening（P0.05）.The failure rate of ALT in 2010 was lower than that in 2008 and 2009（P0.01）.Alcohol and fatigue before blood donation could lead to ALT failure.Conclusion ALT screening before blood donation can not only protect the health of blood donors,but also avoid unnecessary waste of blood,therefore saving blood resources.