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脂立平颗粒对大鼠血脂及血液流变学的影响
引用本文:张诚光,罗霄山,谭树教,陈玉兴.脂立平颗粒对大鼠血脂及血液流变学的影响[J].中国医药导报,2008,5(20):16-17.
作者姓名:张诚光  罗霄山  谭树教  陈玉兴
作者单位:1. 广东省第二中医院,广东广州,510095
2. 广东省人民医院,广东广州,510080
3. 广东省中医研究所,广东广州,510060
摘    要:目的:探讨脂立平颗粒对脂肪肝大鼠血脂和血液流变学的影响。方法:采用复合方式建立大鼠脂肪肝模型,观察给药结束后不同组别大鼠血清TC、TG、ALT含量及肝组织TC、TG、HDL、LDL含量;同时检测全血高、中、低切黏度、血浆黏度。结果:脂立平颗粒可显著降低降低肝组织及血浆中TC、TG含量,显著降低全血黏度、血浆黏度。结论:脂立平颗粒对脂肪肝大鼠血脂及血液流变学有明显调节作用。

关 键 词:脂立平颗粒  血脂  血液流变学

The effect of Zhiliping on the blood lipid and hemorrheology of fatty liver rat
ZHANG Cheng-guang,LUO Xiao-shan,TAN Shu-min,CHEN Yu-xing.The effect of Zhiliping on the blood lipid and hemorrheology of fatty liver rat[J].China Medical Herald,2008,5(20):16-17.
Authors:ZHANG Cheng-guang  LUO Xiao-shan  TAN Shu-min  CHEN Yu-xing
Affiliation:ZHANG Cheng-guang, LUO Xiao-shan, TAN Shu-min, CHEN Yu-xing (1.The Second Hospital of Traditional Chinese Medicine of Guangdong Province, Guangzhou 510095,China; 2.Guangdong Provincial People's Hospital, Guangzhou 510080,China; 3.Institute of Traditional Chinese Medicine of Guangdong Province, Guangzhou 510060,China)
Abstract:Objective: To investigate the effect of Zhiliping on the blood lipid and hemorrheology of fatty liver rat. Methods:Combination mode was used to establish fatty liver rat. Fatty degeneration and blood fat of hepatic tissue were detected by histopathology and biochemics after treatment. At the same time we also detected blood viscosity and plasm viscosity. Results:Zhiliping could obviously lower TG, TC and blood viscosity. It could improve the degree of hepatic steatosis and hepatocellular necrosis of rats. Conclusion: Zhiliping can adjust fatty substance metabolism and lower blood lipid and improve hemorrheology of fatty liver rat.
Keywords:Zhiliping  Blood lipid  Hemorrheology
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