静坐行为和体力活动与血脂异常

目的:分析乌海市居民静坐行为和体力活动与血脂异常的关系.方法:对乌海市11 497名18~79 周岁的常住居民进行横断面研究.通过问卷调查、体格检查、实验室检查收集研究对象人口学信息、静坐行为和体力活动情况、健康状况、血脂指标及其他协变量信息,其中静坐行为和体力活动部分采用国际上广泛使用的国际体力活动问卷(international physical activity questionnaire,IPAQ)长卷测量,在中国人群中信度和效度得到了检验,血脂异常的定义参考《中国成人血脂异常防治指南(2016年修订版)》. 结果:根据IPAQ工作组建议,剔除124名报告的每天体力活动时间超过960 min的研究对象.11 373名纳入分析的研究对象中,静坐时间4 h/d以上占50.58%;体力活动水平低、中等和高的比例分别为23.43%、37.29%和39.28%;血脂异常新发和现患检出率分别为20.46%和16.13%.静坐行为增高女性血脂异常新发风险(OR=1.17, 95% CI:1.00~1.36),增高男女性血脂异常现患风险(OR男=1.21, 95% CI:1.02~1.44;OR女=1.24, 95% CI:1.04~1.48).体力活动与血脂异常关系的分析发现,男性高体力活动水平降低血脂异常现患风险(OR=0.78, 95% CI:0.62~0.98).结论:静坐行为增高血脂异常风险,体力活动降低血脂异常风险.

Associations of sedentary behavior and physical activity with dyslipidemia

Objective:To analyze associations of sedentary behavior and physical activity with dyslipidemia among residents in Wuhai city.Methods: Data about social demographic characteristics, life style, health status and other covariate required for analysis in this study was obtained from a cross-sectional study on a total of 11 497 18-79 years old residents in Wuhai City by questionnaire, body mea-surement and laboratory examination.In this study, sedentary behavior and physical activity were evaluated using international physical activity questionnaire long version (IPAQ).IPAQ is widely used all over the world, and its reliability and validity have been tested in Chinese population.2016 Chinese Guideline for the Management of Dyslipidemia in Adults was used to define dyslipidemia in this study.Results: According to IPAQ scoring protocol, 124 participants were excluded as a result of reporting more than 960 min of physical activity per day.50.58% of 11 373 participants included in the analysis reported more than 4 hours of sedentary behavior per day in this study, thus 49.42% participants reported no more than 4 hours of sedentary behavior per day;the proportions of these 11 373 participants who reached Low level physical activity, Moderate level physical activity and high level physical activity were 23.43%, 37.29% and 39.28% respectively;and the detection ratios of new cases and prevalent cases of dyslipidemia in Wuhai City were 20.46% and 16.13% respectively.After controlling for confounders in this study, we found out that sedentary behavior increased the risk of new cases of dyslipidemia in women (OR=1.17, 95% CI: 1.00-1.36), and increased the risk of prevalent cases of dyslipidemia in both men (OR=1.21, 95% CI: 1.02-1.44) and women (OR=1.24, 95% CI: 1.04-1.48);as for association of physical activity with dyslipidemia, association was found between high level physical activity and prevalent cases of dyslipidemia in men in this study (OR=0.78, 95% CI: 0.62-0.98), suggested that high level physical activity may help to reduce the risk of prevalent cases of dyslipidemia in men.Conclusion: Our results from this cross-sectional study in Wuhai City suggested that sedentary behavior increased the risk of dyslipidemia;by contrast, physical activity may help to reduce the risk of dyslipidemia.