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Further flavonol and iridoid glycosides from Ajuga remota aerial parts
Authors:LAWRENCE ONYANGO AROT Manguro  JOSEPH ACHOLA Ogur  DENNIS MAGIO Okora  SAMUEL OTIENO Wagai  PETER Lemmen
Affiliation:  a Chemistry Department, Maseno University, Maseno, Kenya b Botany Department, Maseno University, Maseno, Kenya c Technische Universitaet Muenchen, Institut fuer Organische Chemie und Biochemie, Garching, Germany
Abstract:Five new iridoid glycosides characterised as 6-keto-8-acetylharpagide (1), 6,7-dehydro-8-acetylharpagide (2), 7,8-dehydroharpagide (3), 8-acetylharpagide-6-O-β-glucoside (4), harpagide-6-O-β-glucoside (5) together with three flavonol glycosides, myricetin 3-O-rutinoside-4'-O-rutinoside (6), myricetin 3-O-rutinoside-3'-O-rutinoside (7) and isorhamnetin 3-O-rutinoside-7-O-rutinoside-4'-O-β-glucoside (8) have been isolated from the aerial parts of Ajuga remota. Also isolated were two known compounds ajugarin IV and ajugarin V. Their structures were established using spectroscopic methods including UV, IR, FAB-MS, HR-MS, 1D and 2D NMR techniques.
Keywords:Ajuga remota  Labiatae  Iridoid glycosides  Flavonol glycosides
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