肝硬化并发上消化道出血的危险因素分析

目的探讨肝硬化并发上消化道出血的相关危险因素。方法选择2010年1月至2013年12月在我院治疗的150例肝硬化患者为研究对象,将其中并发上消化道出血的86例定为观察组,其余64例定为对照组,对两组患者的临床资料进行对比分析。结果两组的静脉曲张发生率差异有统计学意义(P<0.05)、肝功能分级差异有统计学意义(P<0.05)、门静脉高压发生率差异有统计学意义(P<0.05)、脾静脉内径、门静脉内径差异有统计学意义(P<0.05),但两组的性别、年龄、病程等一般资料的差异无统计学意义(P>0.05)。结论食管胃府静脉曲张程度、肝功能分级、门静脉压力、门脾静脉内径均为肝硬化并发上消化道出血的相关因素,对高危患者进行积极的干预措施,对预防和治疗肝硬化的严重并发症具有重要意义。

Analysis of Risk Factors of Hepatic Cirrhosis with Upper Gastrointestinal Bleeding

Objective To analyze the related risk factors of liver cirrhosis with upper gastrointestinal hemorrhage. Methods 150 patients with cirrhosis from January 2010 to December 2010 in our hospital were selected and divided into two groups according to whether they suffered from upper gastrointestinal hemorrhage （the observation group, with 86 patients in it） or not （the control group, with 64 patients in it）. The primary outcome was a comparative analysis of their clinical data. Results Differences of the incidence of varicosity, rank liver function, the incidence of portal hypertension, and the differences of splenic vein diameter, portal vein diameter were statistically significant （P〈0.05）. The general data such as gender, age and course of disease of the the two groups were of no statistical significance （P〉0.05）. Conclusions Cirrhosis with upper gastrointestinal bleeding are relevant to the degree of esophagogastric varicosity, rank of liver function, portal blood pressure, and splenic vein diameter, portal vein diameter. Applying positive intervention measures for the high-risk patients is significant to prevent and treat the serious complications of liver cirrhosis.