急性腔隙性脑梗死患者脑白质疏松磁共振影像分层研究

目的 通过分析腔隙性脑梗死患者脑白质疏松磁共振成像（magnetic resonance imaging，MRI）特点并结合脑白质血液供应，探讨影像学分层的临床价值。 方法 连续选取北京天坛医院住院的合并脑白质疏松的急性腔隙性脑梗死患者61例，按其脑白质疏松部位不同分为3组（皮层下组、室旁组和混合组），按其脑白质疏松的严重程度分为3级，分析各组患者临床一般资料的特点及各组、各级脑白质疏松MRI特点。 结果 皮层下组患者年龄较室旁组及混合组小，其差异具有统计学意义（P<0.05）。腔隙性脑梗死患者中，深部、室旁白质疏松及深部合并室旁白质疏松共占88.50%，而皮层下白质疏松占11.50%。深部/室旁白质疏松以2级常见，皮层下白质疏松以1级最常见。 结论 腔隙性脑梗死患者脑白质疏松随年龄增加而加重，而且其脑白质疏松多发生在深部和或室旁白质。

Magnetic Resonance Imaging Stratification in Acute Lacunar Infarction with Leukoaraiosis

Objective To investigate clinical value of magnetic resonance imaging (MRI) stratification, through analysing MRI characters of leukoaraiosis and blood supply of cerebral white matter in patients with acute lacunar infarction.
Methods Sixty-one consecutive with acute lacunar infarction inpatients were included. The patients were divided into three groups(subcortical group, periventricular group and mixed group) according to the location of leukoaraiosis. We discussed characteristic appearances of leukoaraiosis in MRI and clinical data.
Results The patients in subcortical group were younger than the other two groups(P<0.05). High frequency(total 88.50%) of deep or/and periventricular white matter lesion was detected in lacunar infarction patients. In periventricular group and mixed group, grade two presentation was the most common presentation(52.45%), and in subcortical group, grade one presentation was the most common presentation(54.10%).
Conclusion Progression of leukoaraiosis was associated with aging in patients with lacunar infarction.