| Synthesis of calixarenes and their extraction performance for ester catechins |
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| 作者姓名： | 易健民 黄赛金 唐课文 黄可龙 |
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| 作者单位： | Department of Chemistry and Chemical Engineering Hunan Institute of Science and Technology，School of Chemistry and Chemical Engineering Central South University，Department of Chemistry and Chemical Engineering Hunan Institute of Science and Technology，School of Chemistry and Chemical Engineering Central South University，Yueyang 414000 China School of Chemistry and Chemical Engineering Central South University Changsha 410083 China，Changsha 410083 China，Yueyang 414000 China，Changsha 410083 China |
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| 摘 要： | A series of extractants (tert-butylcalix6]arene, tert-butylcalix8]arene and octeacetate of tert-butylcalix8]arene) were synthesized, and their structures were identified by IR and 1H-NMR. The distribution behavior of ester catechins monomer in the aqueous and chloroform two-phase system containing one of calixarene was studied. The influences of different extractants, concentration of tert-butylcalix8]arene and extraction temperature on the partition coefficients and the separation factors were investigated. The experiment results show that tert-butylcalix8]arene is the best extractant that forms a more stable supramolecular compound with gallocatechin gallate (GCG) than with epigallocathechin gallate (EGCG) or epicatechin gallate (ECG). When the concentration of p-tert-butylcalix8]arene is 3.79 mmol/L, the extraction temperature is 4 ℃, the partition coefficients of KGCG, KECG, KEGCG are 0.987, 0.629, 0.449,the separation factors of α1 and α2 are 1.450 and 1.596, respectively. The important factors influencing the extraction properties of calixarene are discovered to be its cavity size and hydrogen bonding.
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| 关 键 词： | 酯儿茶素单体 萃取 芳烃 合成方法 |
| 收稿时间： | 2 March 2007 |
| 修稿时间： | 2007-03-02 |
Synthesis of calixarenes and their extraction performance for ester catechins |
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| Yi Jian-min , Huang Sai-jin , Tang Ke-wen and Huang Ke-long.Synthesis of calixarenes and their extraction performance for ester catechins[J].Journal of Central South University of Technology,2007,14(6):798-802. |
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| Authors: | Yi Jian-min Huang Sai-jin Tang Ke-wen and Huang Ke-long |
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| Affiliation: | 1. Department of Chemistry and Chemical Engineering, Hunan Institute of Science and Technology, Yueyang 414000, China; 2. School of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China |
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| Abstract: | A series of extractants (tert-butylcalix6]arene, tert-butylcalix8]arene and octeacetate of tert-butylcalix8]arene) were
synthesized, and their structures were identified by IR and 1H-NMR. The distribution behavior of ester catechins monomer in the aqueous and chloroform two-phase system containing one
of calixarene was studied. The influences of different extractants, concentration of tert-butylcalix8]arene and extraction
temperature on the partition coefficients and the separation factors were investigated. The experiment results show that tert-butylcalix8]arene
is the best extractant that forms a more stable supramolecular compound with gallocatechin gallate (GCG) than with epigallocathechin
gallate (EGCG) or epicatechin gallate (ECG). When the concentration of p-tert-butylcalix8]arene is 3.79 mmol/L, the extraction temperature is 4 °C, the partition coefficients of K
GCG, K
ECG, K
EGCG are 0.987, 0.629, 0.449, the separation factors of a
1 and a
2 are 1.450 and 1.596, respectively. The important factors influencing the extraction properties of calixarene are discovered
to be its cavity size and hydrogen bonding.
Foundation item: Project (20576029) supported by the National Natural Science Foundation of China |
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| Keywords: | calixarene synthesis ester catechin monomer extraction |
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