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西地那非对高原移居青年血流动力学的影响
引用本文:王伟,马广全,李彬,曹荣成,胡华,崔建华,哈振德,高亮.西地那非对高原移居青年血流动力学的影响[J].临床军医杂志,2008,36(4).
作者姓名:王伟  马广全  李彬  曹荣成  胡华  崔建华  哈振德  高亮
作者单位:解放军第18医院,新疆,叶城,844900
摘    要:目的探讨西地那非对高原移居青年血流动力学的影响。方法把进驻海拔3700m半年的20名青年随机分为两组,每组10人,一组为服药组,另一组为对照组。两组在服药1h后分别用XG-Ⅲ型血液循环功能自动测试仪检测血流动力学。结果服药组较对照组P、TPR、ALT、η、PAWP、CCP降低,差异有统计学意义(P(0.05);SV、mAP、BK、BV增高,差异有统计学意义(P(0.05)。结论服用西地那非对高原移居青年血流动力学有明显的改善作用。

关 键 词:高海拔  西地那非  血流动力学

Effect of Sildenafil on Hemodynamics of Migrants at High Altitude
Wang Wei,Ma Guang-quan,Li Bin,Cao Rong-cheng,Hu Hua,Cui Jian-hua,Ha Zhen-de,Gao Liang.Effect of Sildenafil on Hemodynamics of Migrants at High Altitude[J].Clinical Journal of Medical Officer,2008,36(4).
Authors:Wang Wei  Ma Guang-quan  Li Bin  Cao Rong-cheng  Hu Hua  Cui Jian-hua  Ha Zhen-de  Gao Liang
Affiliation:Wang Wei,Ma Guang-quan,Li Bin,Cao Rong-cheng,Hu Hua,Cui Jian-hua,Ha Zhen-de,Gao Liang (PLA 18th Hospita,Yecheng 844900,China)
Abstract:Objective To explore the effect of sildenafil on the hemodynamics in migrants at high altitude. Methods In a randomized trial, 20 subjects who had migrated to an altitude of 3,700 meters were divided into drug group (n=10) and control group (n=10), and then their hemodynamics was detected using type XG-III blood circulation function tester after administration of medicine for one hour.Results Compared with that in the control group, pulse rate (HR), total peripheral resistance (TPR), ALT, η (viscosity), pulmonary artery wedge pressure (PAWP) and CCP reduced and stroke volume (SV), mean artery pressure (mAP), BK and blood volume (BV) increased significantly in the drug group (P<0.05).Conclusion Sildenafil can improve hemodynamics of migrants at high altitude.
Keywords:high altitude  sildenafil  hemodynamics  
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