101例药品不良反应报告分析

目的：了解我院药品不良反应（ADR）发生特点及引发的相关因素，促进临床合理用药。方法：对我院2006年1月1日-2007年11月20日收集到的101例ADR报告分别从药物种类、抗感染药物类别、给药途径及患者年龄等方面进行统计分析。结果：101例不良反应中，涉及抗菌药物72例，占71.29％；中药注射剂8例，占7 .92％；静脉给药引起的不良反应81例，占80.20％。不良反应最常见的表现为皮肤及其附件损害。结论：应合理使用抗感染药物及中药注射剂，加强对中药注射剂的质量监测,避免或减少ADR重复发生。

Adverse drug reactions analysis of 101 cases

Objective: To understand the characteristics of adverse drug reactions(ADR)and promote the rational use of drugs in clinic. Methods: The 101 ADR cases had been collected from Jan.1.2006 to Nov.20.2007 in our hospita1. All the cases were ana-lyzed in respect of drug species,categories of anti-infective drugs,administration and the patients' age. Results: Of 101 ADR cases,72 cases about antibiotics accounted for 71.29% and 8 cases about traditional chinese medicine injections accounted for 7.92%. ADR induced by intravenous injection were 81 cases (80.20%). ADR were mainly manifested as skin and local lesion. Conclusion: Rational use of anti-infective drugs and the good quality of the traditional chinese medicine injection should be emphasized to decrease the oc-currence of ADR.