头孢他啶致精神异常

1例52岁女性患者,因肺结核合并结核性胸膜炎,给予左氧氟沙星、利福霉素钠、异烟肼、乙胺丁醇及吡嗪酰胺联合治疗。治疗第13天痰培养报告:阴沟肠杆菌阳性。遂加用头孢他啶2 g溶于0.9%氯化钠注射液100 ml,1次/d静脉滴注。4 d后患者出现意识模糊,胡言乱语,停用左氧氟沙星,精神症状无好转;停用头孢他啶,继续使用其他药物,精神症状消失,未再应用头孢他啶,上述症状未再出现。再次给予患者左氧氟沙星,未出现精神症状。

Psychiatric disorder due to ceftazidime

A 52-year-old female patient received combination treatment with levofloxacin,rifamycin sodium,isoniazid,ethambutol and pyrazinamide for pulmonary tuberculosis accompanied by tuberculous pleurisy.On day 13 of treatment,her sputum culture was positive for Enterobacter cloacae.Subsequently,an IV infusion of ceftazidime 2 g in 0.9% sodium chloride 100 ml once daily was added to her regimen.Four days later,the patient experienced confusion and delirious.Levofloxacin was stopped,but his psychiatric symptoms did ...