细针穿刺肝脏孤立性坏死结节的临床病理特征

目的研究B超下穿刺肝孤立性坏死结节的临床及病理学特点。方法收集32例肝孤立性坏死结节的临床资料,并在光镜下观察其细针穿刺组织病理形态,同时复习相关文献。结果本组男性21例,女性11例,平均年龄46.8岁,结节直径0.8~4.0 cm,临床及影像学缺少特异表现,光镜下结节中央为凝固性坏死,坏死外周围绕着一层弹力纤维及胶原组织,伴少数炎细胞浸润,结节周围的肝细胞基本正常。结论肝孤立性坏死结节是一种少见的非肿瘤性结节状病变,对B超引导下穿刺标本进行组织病理学观察能够准确诊断。

Clinicopathologic Features of Solitary Necrotic Nodules of Liver by Fine Needle Aspiration Biopsy

Objective To study clinical and pathologic features of solitary necrotic nodule of the liver by fine needle aspiration biopsy.Methods We collected the clinical data of hepatic solitary necrotic nodule of 32 cases and observed their needle aspiration biopsy specimens by light microscope.Meanwhile,pertinent literature was reviewed.Results Of the 32 cases,21 were males and 11 were females,with a mean age of 46.8 years.The diameter of the nodules was from 0.8 to 4(cm).Their clinical and imaging features were not specific.Solitary necrotic nodules of the livers were composed of a central coagulation necrosis surrounded by a peripheral hyaline fibrotic capsule with a few of inflammatory cells.There were not obvious variances in the peripheral hepatocytes.Conclusion Solitary necrotic nodule of the liver is a rare nonneoplastic lesion of the liver.It is absolutely significant to diagnose solitary necrotic nodule of the liver by fine needle aspiration under the guidance of B-ultrasonic.