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持续肾脏替代治疗的重症感染患者应用万古霉素的药学监护
引用本文:孙浩,庞露,徐英宏,菅凌燕,肇丽梅.持续肾脏替代治疗的重症感染患者应用万古霉素的药学监护[J].中国药房,2012(32):3030-3032.
作者姓名:孙浩  庞露  徐英宏  菅凌燕  肇丽梅
作者单位:中国医科大学附属盛京医院药学部,沈阳110004
摘    要:目的:探讨持续肾脏替代治疗(CRRT)重症感染患者应用万古霉素的药学监护方法。方法:临床药师参与1例CRRT重症感染患者的万古霉素监护实践,辅助医师进行药物剂量和给药方案调整。结果:对CRRT患者进行万古霉素血清药物浓度测定,可以优化万古霉素剂量调整方案。结论:临床药师通过开展万古霉素血清药物浓度测定,能够提高万古霉素剂量调整的合理性。

关 键 词:万古霉素  持续肾脏替代治疗  监护  临床药师  危重症

Pharmaceutical Care of Vancomycin for a CRRT Patient with Severe Infection
SUN Hao,PANG Lu,XU Ying-hong,JIAN Ling-yan,ZHAO Li-mei.Pharmaceutical Care of Vancomycin for a CRRT Patient with Severe Infection[J].China Pharmacy,2012(32):3030-3032.
Authors:SUN Hao  PANG Lu  XU Ying-hong  JIAN Ling-yan  ZHAO Li-mei
Affiliation:(Dept. of Pharmacy, Shengjing Hospital of China Medical University, Shenyang 110004, China)
Abstract:OBJECTIVE: To study the pharmaceutical care of vancomycin for CRRT (continuous renal replacement therapy) pa- tient with severe infection. METHODS: Clinical pharmacist assisted physician to adjust the dose and medication program, based on the monitoring of vancomycin for a CRRT patient with severe infection. RESULTS: The serum concentration of drug was deter- mined so as to optimize the dose of vancomycin and adjust drug program. CONCLUSION: Clinical pharmacists help to improve the rationality of vancomycin dose adjustment through determination of vancomycin concentration in serum.
Keywords:Vancomycin  Continuous renal replacement therapy  Monitoring  Clinical pharmacist  Critically ill
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