| Vasohibin-1与肿瘤 |
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| 引用本文： | 赵广宁,丁娜,孙岩,韩瑞发.Vasohibin-1与肿瘤[J].国际肿瘤学杂志,2013,40(4):252-255. |
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| 作者姓名： | 赵广宁 丁娜 孙岩 韩瑞发 |
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| 作者单位： | 天津市泌尿外科研究所肿瘤分子遗传学研究室, 天津医科大学第二医院泌尿外科,300211 |
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| 摘 要： | Vasohibin-1(VASH1)是新近发现的在血管内皮细胞中由血管内皮生长因子(VEGF)、成纤维生长因子-2(FGF-2)等诱导产生的具有负反馈调节血管生成作用的蛋白因子.近年来研究表明,VASH1在多种肿瘤血管生成中扮演着重要的角色,提示其有望成为相关肿瘤诊断和治疗的分子标志物以及分子靶向治疗的有效蛋白因子.
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| 关 键 词： | 肿瘤 血管生成 Vasohibin-1 |
Vasohibin-1 and tumor |
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| ZHAO Guang-ning
,
DING Na
,
SUN Yan
,
HAN Rui-fa.Vasohibin-1 and tumor[J].Journal of International Oncology,2013,40(4):252-255. |
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| Authors: | ZHAO Guang-ning DING Na SUN Yan HAN Rui-fa |
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| Affiliation: | Department of Urology, Second Hospital of Tianjin Medical University, Tumor Molecular Genetics Laboratory, Tianjin Institute of Urology, Tianjin 300211, China |
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| Abstract: | Vasohibin-1(VASH1),which is induced in response to angiogenic stimuli such as vascular endothelial growth factor (VEGF) and fibroblast growth factor (FGF)-2, has recently been isolated as a novel negative feedback inhibitor of angiogenesis.Several studies have demonstrated that VASH1 plays important roles in the development of various tumors and it would potentially be a biomarker and a candidate for molecular targeted therapy for patients with cancer in the future. |
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| Keywords: | Neoplasms Angiogenesis Vasohibin-1 |
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