补血醒脑汤联合常规西药治疗气虚血瘀型恢复期脑梗死临床研究

目的:观察自拟补血醒脑汤联合常规西药治疗气虚血瘀型恢复期脑梗死的临床疗效。方法:将70例气虚血瘀型恢复期脑梗死患者按照随机数字表法分为对照组和观察组,每组各35例。对照组给予西药对症治疗,观察组在对照组的基础上加用自拟补血醒脑汤。比较两组患者的临床疗效及治疗前后中医证候积分、神经功能缺损评分美国国立卫生研究院卒中量表(national institutes of health stroke scale,NIHSS)、Barthel指数(Barthel index,BI)、生活质量综合评定问卷(generic quality of life inventory-74,GQOLI-74)],检测两组患者治疗前后血液流变学指标变化情况。结果:对照组优良率为71.43%,观察组优良率为88.57%,两组患者优良率比较,差异具有统计学意义(P<0.05)。两组患者治疗后中医证候积分、血液流变学指标、NIHSS评分低于治疗前,且观察组治疗后低于对照组,差异具有统计学意义(P<0.05)。两组患者治疗后BI评分、GQOLI-74评分高于治疗前,且观察组治疗后高于对照组,差异具有统计学意义(P<0.05)。结论:补血醒脑汤联合常规西药治疗气虚血瘀型恢复期脑梗死,可改善患者临床症状、血液黏滞状态及神经损伤程度。

Clinical Study of Buxue Xingnao Decoction Combined with Conventional Western Medicine in the Treatment of Cerebral Infarction in the Recovery Stage of Qi Deficiency and Blood Stasis Type

Objective:To observe the clinical effect of Buxue Xingnao Decoction(补血醒脑汤,BXXND)combined with conventional western medicine in the treatment of cerebral infarction in recovery stage of qi deficiency and blood stasis type.Method:70 patients with cerebral infarction in recovery stage of qi deficiency and blood stasis type were divided into control group and observation group according to the method of random number table,with 35 cases in each group.The control group was treated with western medicine,and the observation group was treated with self-made Buxue Xingnao Decoction on the basis of the control group.The clinical efficacy,TCM syndrome score,neurological deficit score(national institutes of health stroke scale,NIHSS),Barthel index(BI)and Generic Quality of Life Inventory-74(GQOLI-74)before and after treatment were compared between the two groups.Changes of hemorheology indexes before and after treatment in two groups were detected.Results:The excellent rate of the control group was 71.43%,and that of the observation group was 88.57%,the difference between the two groups was statistically significant(P<0.05).After treatment,the TCM syndrome score,hemorheology index and NIHSS score of the two groups were lower than before treatment,the observation group was lower than the control group after treatment,and the difference between the two groups was statistically significant(P<0.05).After treatment,Bi score and GQOLI-74 score of the two groups were higher than before treatment,the observation group is higher than the control group after treatment,the difference was statistically significant(P<0.05).Conclusion:Buxue Xingnao Decoction combined with conventional western medicine can improve the clinical symptoms,blood viscosity and nerve injury of patients with cerebral infarction in the recovery stage of qi deficiency and blood stasis type.