| 复方奥硝唑中空栓的制备及质量控制 |
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| 引用本文： | 王彦,张利利.复方奥硝唑中空栓的制备及质量控制[J].中国现代应用药学,2009,26(3):224-226. |
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| 作者姓名： | 王彦 张利利 |
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| 作者单位： | 1.天津医科大学总医院,天津 300052;2.天津医科大学药学院,天津 300070 |
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| 摘 要： | 目的制备复方奥硝唑中空栓剂,并建立质量控制方法。方法以混合脂肪酸甘油酯为基质制备中空栓剂;采用等吸收-双波长法同时测定其主药奥硝唑和左氧氟沙星的含量;对制剂进行卫生学、刺激性及稳定性等试验。结果奥硝唑和左氧氟沙星的平均回收率（n=9）分别为99.7%,100.2%,其他各项检查均符合栓剂的有关规定。结论本制剂制备工艺简单,性质稳定,质量可控。
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| 关 键 词： | 奥硝唑 左氧氟沙星 中空栓 质量控制 |
| 收稿时间： | 1/1/1900 12:00:00 AM |
Preparation and Quality Control of Compound Ornidazole Hollow Type Suppository |
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| WANG Yan,ZHANG Lili.Preparation and Quality Control of Compound Ornidazole Hollow Type Suppository[J].The Chinese Journal of Modern Applied Pharmacy,2009,26(3):224-226. |
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| Authors: | WANG Yan ZHANG Lili |
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| Affiliation: | 1.General Hospital of Tianjin medical Univerity,Tianjin 300052,China;2.School of Pharmacy,Tianjin Medical University,Tianjin 300070,China |
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| Abstract: | OBJECTIVE To observe the effects of excipient on the sterile stability of Ioxilan Injection. METHODSThe pH values,free iodide,chromatographic purity and the contents of Ioxilan Injection were measured. The change were calculated before and after steriliza |
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| Keywords: | excipient Ioxilan Injection stability |
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