| 人体胚胎干细胞蛋白质组学的研究进展 |
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| 引用本文： | 眭维国,谭秋培,薛雯,陈洁晶.人体胚胎干细胞蛋白质组学的研究进展[J].医学综述,2012,18(23):3939-3941. |
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| 作者姓名： | 眭维国 谭秋培 薛雯 陈洁晶 |
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| 作者单位： | 1. 中国人民解放军第181医院肾脏科全军肾移植与透析治疗中心广州军区肾脏疾病研究所广西代谢性疾病研究重点实验室,广西桂林,541002
2. 广西师范大学生命科学学院,广西桂林,541004 |
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| 基金项目： | 国家"重大新药创新"科技重大专项课题 |
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| 摘 要： | 人体胚胎干细胞是一类具有自我更新能力的多潜能细胞,在一定条件下,可分化成超过200种人体细胞类型,它在发育生物学和再生医学中具有重要的研究价值。其多潜能性使得一系列疾病,包括癌症、阿尔茨海默病和帕金森病的治疗看到了希望。而胚胎干细胞蛋白质组学的研究对揭示胚胎干细胞增殖和分化的机制以及其多潜能的维持具有重大意义。在此,总结在过去几年中已报道的部分关于人体胚胎干细胞蛋白质组学研究取得的进步及其对人体胚胎干细胞研究的促进作用。
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| 关 键 词： | 人体胚胎干细胞 蛋白质组 蛋白质组学 |
Research Progress of human embryonic stem cells hESC Proteomics |
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| SUI Wei-guo
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TAN Qiu-pei
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XUE Wen
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CHEN Jie-jing.Research Progress of human embryonic stem cells hESC Proteomics[J].Medical Recapitulate,2012,18(23):3939-3941. |
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| Authors: | SUI Wei-guo TAN Qiu-pei XUE Wen CHEN Jie-jing |
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| Affiliation: | 1.(1.Nephrology Department,Guilin 181st Hospital,Guangxi Key Laboratory of Metabolic Diseases Research,Guilin 541002 China;2.College of Life Science,Guangxi Normal University,Guilin 541004,China) |
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| Abstract: | Human embryonic stem cell(hESC)is a group of pluripotent cells with self-renewal capacity,which can differentiate into more than 200 kinds of human cell types under certain conditions,and has important research value in developmental biology and regenerative medicine.Pluripotency makes cure of a range of diseases such as cancer,Alzheimer disease and Parkinson disease possible.Embryonic stem cell proteomics research plays an important role in revealing embryonic stem cell proliferation and differentiation mechanisms as well as the maintenance of the pluripotent.Here is to make a summary of some research achievements of human embryonic stem cells proteomics and their role in promoting research in hESC reported in the past few years. |
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| Keywords: | Embryonic stem cells Proteome Proteomics |
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