金龙固本补肺健脾合剂对哮喘控制测试评分的影响

目的:观察金龙固本补肺健脾合剂治疗哮喘缓解期疗效及对哮喘控制测试评分的影响。方法:收集支气管哮喘缓解期宿痰伏肺兼肺脾气虚证型患者239例,随机分为中药治疗组121例,空白对照组118例,中药治疗组给予金龙固本补肺健脾合剂口服,空白对照组不进行药物干预,疗程4个月,随访12个月。观察哮喘控制测试(ACT)评分、哮喘ACT控制情况、中医证候评分及肺通气功能等指标,所有数据采用SAS 8.1统计分析软件进行统计学处理。结果:患者ACT评分,治疗组升高明显(P0.05)具有显著性差异;中医证候评分和1秒钟用力呼气量(FEV1)改善情况与ACT表评分结果有良好相关性。结论:金龙固本补肺健脾合剂能明显改善哮喘缓解期症状,改善患者ACT评分,减少急性发作,临床疗效明显。

Effect of Jinlong Guben Bufei Jianpi Mixture on Asthma Control Test Scores

Objective: To observe the effect of Jinlong Guben Bufei Jianpi mixture in treating asthma in the remission stage and the asthma control test (ACT) scores. Method: Inthis study, two hundred and thirty-nine patients with bronchialasthma in the remission stage (insidious sputum in lungs andlung and spleen qi deficiencysyndromes) were collected andrandomly divided into the traditional Chinese medicine(TCM)treatment group (121 cases) and the blank control group (118 cases). The cases in the TCM treatment group took Jinlong Guben Bufei Jianpi mixture for 4 months, while the cases in the blank control group were given no medical intervention.All of them were followed up for 12 months. During the study, ACT scores, asthma ACT control, TCM syndrome scores, pulmonary ventilation functionand other indexes were observed. All data was statistically analyzed by using SAS 8.1 software. Result: According to ACT scores for the patients, the treatment group was significantly higher than the blank control group (P <0.05). There were good correlations among TCM syndrome scores,forced expiratory volume in one second(FEV₁)improvement and ACT scores. Conclusion: Jinlong Guben Bufei Jianpi mixture can relieve asthma symptoms of in the remission stage, andincrease ACT scores, reduce acute attacks, with obvious curative effect.