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肾血管性高血压时原癌基因c—fos在肾上腺内的表达
引用本文:高峻钰,刘少君.肾血管性高血压时原癌基因c—fos在肾上腺内的表达[J].第四军医大学学报,1992,13(6):438-440.
作者姓名:高峻钰  刘少君
作者单位:西京医院肾脏病科 (高峻钰,李元勋),第四军医大学神经生物学研究室 (刘少君),第四军医大学神经生物学研究室(张遐)
摘    要:

关 键 词:肾性高血压  肾上腺皮质  免疫学

Expression of c-fos oncogenes in the corticoadrenal of the rat with renal hypertension
GAO Jun-Yu LI Yuan-Xun LIU Shao-Jun and ZHANG Xia.Expression of c-fos oncogenes in the corticoadrenal of the rat with renal hypertension[J].Journal of the Fourth Military Medical University,1992,13(6):438-440.
Authors:GAO Jun-Yu LI Yuan-Xun LIU Shao-Jun and ZHANG Xia
Affiliation:GAO Jun-Yu LI Yuan-Xun LIU Shao-Jun and ZHANG Xia Department of Nephrology,Xijing Hospital Department of Neurobiology
Abstract:A model of renal hypertension was established through ligaturing one of the renal artery in the rat. An antiserum against Fos oncoprotein was used to detect immunohistochemically the activated cells of the corti coadrenal. A lot of Fos irnmunoreactive (ir) nuclei were demonstrated in the zona glomeralose. Few of labeled nuclei were seen in the lateral part of the zona fasciculata. An increasing number of Fos-ir nuclei were observed in the intermediate part of the zona fksciculata. The highest concentration of labeled nuclei in the inner part of the zona fasciculata. Scattered Fos-ir nuclei existed in the zona reticularis. The labeled nuclei were different in size and often round or oval in form.
Keywords:i renal hypertension  corticoadrenal  Fos  immunohistochemistry  rats  
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