Dual-energy contrast-enhanced digital mammography: Glandular dose estimation using a Monte Carlo code and voxel phantom |
| |
| Affiliation: | 1. Department of Biostatistics and Epidemiology, University of Massachusetts Amherst, Amherst, MA 01003, USA;2. Department of Anthropology, University of Massachusetts Amherst, Amherst, MA 01003, USA;3. Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD 20892, USA;4. Channing Division of Network Medicine, Department of Medicine, Brigham and Women''s Hospital and Harvard Medical School, Boston, MA 02115, USA;5. Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA;6. Division of Preventive Medicine, Brigham and Women''s Hospital and Harvard Medical School, Boston, MA 02215, USA;7. Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA;8. Department of Health Promotion and Policy, University of Massachusetts Amherst, Amherst, MA 01003, USA;1. National Research Council, Institute of Biostructures and Bioimaging, Napoli, Italy;2. Department of Advanced Biomedical Sciences, Federico II University School of Medicine, Naples, Italy |
| |
| Abstract: | PurposeTo estimate the mean glandular dose of contrast enhanced digital mammography, using the EGSnrc Monte Carlo code and female adult voxel phantom.MethodsAutomatic exposure control of full field digital mammography system was used for the selection of the X-ray spectrum and the exposure settings for dual energy imaging. Measurements of the air-kerma and of the half value layers were performed and a Monte Carlo simulation of the digital mammography system was used to compute the mean glandular dose, for breast phantoms of various thicknesses, glandularities and for different X-ray spectra (low and high energy).ResultsFor breast phantoms of 2.0–8.0 cm thick and 0.1–100% glandular fraction, CC view acquisition, from AEC settings, can result in a mean glandular dose of 0.450 ± 0.022 mGy ?2.575 ± 0.033 mGy for low energy images and 0.061 ± 0.021 mGy – 0.232 ± 0.033 mGy for high energy images. In MLO view acquisition mean glandular dose values ranged between 0.488 ± 0.007 mGy – 2.080 ± 0.021 mGy for low energy images and 0.065 ± 0.012 mGy – 0.215 ± 0.010 mGy for high energy images.ConclusionThe low kV part of contrast enhanced digital mammography is the main contributor to total mean glandular breast dose. The results of this study can be used to provide an estimated mean glandular dose for individual cases. |
| |
| Keywords: | CEDM Dosimetry Monte Carlo Breast Mammography Voxel phantom |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
