Cirrhotic patients and older people |
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Authors: | Paul Carrier Marilyne Debette-Gratien J r mie Jacques V ronique Loustaud-Ratti |
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Affiliation: | Paul Carrier, Marilyne Debette-Gratien, Véronique Loustaud-Ratti, Fédération d’Hépatologie, Centre Hospitalier Universitaire Dupuytren de Limoges, Limoges 87042, FrancePaul Carrier, Marilyne Debette-Gratien, Véronique Loustaud-Ratti, Faculté de Médecine et de Pharmacie de Limoges, Rue Docteur Marcland, Limoges 87042, FranceJérémie Jacques, Service de Gastroentérologie, Centre Hospitalier Universitaire Dupuytren de Limoges, Limoges 87042, France |
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Abstract: | The global population is aging, and so the number of older cirrhotic patients is increasing. Older patients are characterised by a risk of frailty and comorbidities,and age is a risk factor for mortality in cirrhotic patients. The incidence of nonalcoholic fatty liver disease as an aetiology of cirrhosis is increasing, while that of chronic viral hepatitis is decreasing. Also, cirrhosis is frequently idiopathic. The management of portal hypertension in older cirrhotic patients is similar to that in younger patients, despite the greater risk of treatment-related adverse events of the former. The prevalence of hepatocellular carcinoma increases with age, but its treatment is unaffected. Liver transplantation is generally recommended for patients 70 years of age. Despite the increasing prevalence of cirrhosis in older people, little data are available and few recommendations have been proposed.This review suggests that comorbidities have a considerable impact on older cirrhotic patients. |
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Keywords: | Liver cirrhosis Portal hypertension Liver cancer Liver transplantation Old age Older Elderly |
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