小剂量胺碘酮联合比索洛尔治疗阵发性房颤的临床观察

目的]观察小剂量胺碘酮联合比索洛尔治疗阵发性房颤的临床效果。方法]选取60例器质性反复发作的阵发性房颤患者,随机分为对照组和治疗组。对照组常规服用胺碘酮,治疗组服用小剂量胺碘酮和比索洛尔,观察治疗结果。结果]两组患者中治疗组的总有效率为76.5%,对照组的总有效率为76.9%,两者疗效相近。在心室率的控制、房颤的复发次数及左室收缩功能方面比较差异无统计学意义(P>0.05)。结论]小剂量胺碘酮联合比索洛尔治疗阵发性房颤疗效与胺碘酮常规量相当,值得临床大样本推广研究。

Low dose Amiodarone combined with Bisoprolol in the treatment of atrial fibrillation

Objective ] To observe the efficiency of low dose amiodarone combined with bisoprolol for paroxysmal atrial fibrillation. Methods ] A group of 60 paroxysmal atrial fibrillation patients were randomly divided into control group and treatment group. The patients in control group were adminstered amiodarone conventionally, and those in treatment group low dose amiodarone combined with bisoprolol. The treatment efficiency was observed. Results] The total efficiency in treatment group was 76.5%, and in control group 76.9%. The treatment efficiency between the two groups was close. There was no significant difference between the two groups in ventricular rate control, number of atrial fibrillation recurrence and left ventricular ejection fraction { P 〉 0.05 ）. Conclusion ] Low-dose amiodarone combined with bisoprolol has equal effect to conventional-dose amiodarone in the treatment of paroxysmal atrial fibrillation. Further studies and larger samples are needed to confirm the results.