| 山蒟化学成分研究(Ⅱ) |
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| 引用本文： | 李书明,韩桂秋,B.H.Arison,M.N.Chang.山蒟化学成分研究(Ⅱ)[J].药学学报,1987,22(3):196-202. |
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| 作者姓名： | 李书明 韩桂秋 B.H.Arison M.N.Chang |
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| 作者单位： | 北京医科大学药学院,*MerckSharp&DohmeResearchLab,USA;MerckSharp&DohmeResearchLab,USA |
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| 摘 要： | 从胡椒科植物山蒟(Piper hancei Maxim)中分得两个新木脂素成分(Ⅰ,Ⅱ)及三个生物碱(Ⅲ,Ⅳ,Ⅴ)。Ⅰ经光谱(IR,UV,MS,1HNMR,13CNMR,APT-13SCNMR,2 D-HNMR)分析等证明其结构为rel-(7 S,8 S,1′R,3′S,4′R)-1′烯丙基-7-(3,4-二甲氧基苯基)-4′-羟基-5′-甲氧基-8-甲基-2′-氧双环3.2.1]辛-5′-烯,为新结构,命名为山蒟醇(hancinol)。经光谱鉴定Ⅱ为burchellin,Ⅲ,Ⅳ,Ⅴ分别为风藤酰胺(futoamide)、荜拨明宁碱(piperlonguminine)和N-异丁基-反-2-反～4-癸二烯酰胺。后四种均首次从该植物中得到。
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| 关 键 词： | 山蒟 新木脂素 生物碱 山蒟醇 Burchellin 风藤酰胺 荜拔明宁碱 N-异丁基-反-2-反-4-癸二烯酰胺 |
| 收稿时间： | 1986-01-02 |
Studies on the chemical constituents of Piper hancei Maxim (II) |
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| LI Shu-Ming,HAN Gui-Aiu,B. H. Arison and M. N. Chang.Studies on the chemical constituents of Piper hancei Maxim (II)[J].Acta Pharmaceutica Sinica,1987,22(3):196-202. |
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| Authors: | LI Shu-Ming HAN Gui-Aiu B H Arison and M N Chang |
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| Abstract: | Two neolignans (Ⅰ, Ⅱ)and three alkaloids (Ⅲ, Ⅳ, Ⅴ) were isolated from Piper hancei Maxim. Ⅰ is a new compound. Its structure was characterized as rel-(7S, 8S, 1′R, 3′S, 4′R)-1′-allyl-7-(3, 4-dimethoxyphenyl)-4′-hydro- xy-5′-methoxy-8-methyl-2′-oxobicyclo 3.2.1] oct-5′-ene by interpretation of UV, IR, 1HNMR,13CNMR, APT-13CNMR, 2 D-HNMR, MS, etc.The others were identified as burchellin (Ⅱ), futoamide (Ⅲ), piperlonguminine (Ⅳ) and N-isobutyl deca-trans-2-trans-4-dienamide (Ⅴ). |
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| Keywords: | Alkaloid Hancinol Futoamide Burchellin Piperlonguminine N-isobutyl deca-trans-2-trans-4-dienamide Piper hancei Maxim Neolignan |
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