| 2,6-二氯苯氧乙酸甲酯合成新工艺 |
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| 引用本文： | 贾洪亮,秦丙昌.2,6-二氯苯氧乙酸甲酯合成新工艺[J].河南化工,2008,25(10):28-29. |
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| 作者姓名： | 贾洪亮 秦丙昌 |
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| 作者单位： | 1. 郑州大学化学系,河南,郑州,450052
2. 安阳师范学院化学化工学院,河南,安阳,455000 |
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| 摘 要： | 以2,6-二氯苯酚、甲醇钠甲醇溶液和氯乙酸甲酯为原料,合成了2,6-二氯苯氧乙酸甲酯。通过实验优化了反应条件,结果发现,当n（2,6-二氯苯酚）∶n（氯乙酸甲酯）=1∶1.3,在加入氯乙酸甲酯之后蒸出2/3甲醇,回流3.5 h即可完成反应,2,6-二氯苯氧乙酸甲酯的收率可达99%以上。用MS、1H NMR及IR对产物结构进行了表征。
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| 关 键 词： | 2 6-二氯苯氧乙酸甲酯 2 6-二氯苯酚 甲醇钠 氯乙酸甲酯 |
New Synthetic Process of Methyl 2,6 -Dichlorophenoxyacetate |
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| JIA Hong-liang,QIN Bing-chang.New Synthetic Process of Methyl 2,6 -Dichlorophenoxyacetate[J].Henan Chemical Industry,2008,25(10):28-29. |
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| Authors: | JIA Hong-liang QIN Bing-chang |
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| Affiliation: | JIA Hong - liang , QIN Bing - chang (1. Department of Chemistry , Zhengzhou University , Zhengzhou 450052 , China ; 2. College of Chemistry and Chemical Engineering , Anyang Normal University , Anyang 455000 , China) |
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| Abstract: | Methyl 2,6 - dichlorophenoxyacetate is prepared with 2,6 - dichlorophenol, sodium methoxide and methyl chloroacetate as raw materials. The reaction conditions are optimized. As a result,the yield of the product is up to 99% when the amount - of - substance ratio of 2,6 - dichlorophenol to methyl chloroacetate is 1 ： 1.3,the 2/3 methanol is distilled off after methyl chloroaeetate have been added,and refluxed for 3 h. The structure of the product is characterized with MS, ^1 H NMR and IR. |
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| Keywords: | methyl 2 6 -dichlorophenoxyacetate 2 6 -dichlorophenol sodium methoxide methyl chloroacetate |
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