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| IL-6 mRNA在脑胶质瘤中的表达及意义 | |
| 引用本文： | 潘德生,王成林,刁宏宇,戚建飞,赵崇智,刘贵军,孙冬弢.IL-6 mRNA在脑胶质瘤中的表达及意义[J].中国医科大学学报,2003,32(3):250-251. |
| 作者姓名： | 潘德生 王成林 刁宏宇 戚建飞 赵崇智 刘贵军 孙冬弢 |
| 作者单位： | 1. 中国医科大学附属第二医院神经外科,辽宁,沈阳,110004 2. 葫芦岛市中心医院神经外科 3. 沈阳医学院附属第二医院神经外科 |
| 摘 要： | 目的 :研究白细胞介素 6 (IL 6 )在人脑胶质瘤发病中的作用和意义。方法 :采用RT PCR半定量法检测IL 6mRNA在 34例胶质瘤及 8例正常脑组织中的表达。结果 :IL 6mRNA在胶质瘤和正常脑组织的表达率分别为 79.4 %和 12 .5 % ,差异十分显著 (P <0 .0 1) ,且与胶质瘤的病理分级相关。结论 :IL 6可能在胶质瘤的发生过程中发挥重要作用。 |
| 关 键 词： | 白细胞介素6 mRNA 胶质瘤 |
| 文章编号： | 0258-4646(2003)03-0250-02 |
| 修稿时间： | 2002年6月27日 |
Expression and Significance of Interleukin-6 mRNA in Gliomas |
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| PAN De-sheng,WANG Cheng-lin,DIAO Hong-yu,QI Jian-fei,ZHAO Chong-zhi,LIU Gui-jun,SUN Dong-tao.Expression and Significance of Interleukin-6 mRNA in Gliomas[J].Journal of China Medical University,2003,32(3):250-251. | |
| Authors: | PAN De-sheng WANG Cheng-lin DIAO Hong-yu QI Jian-fei ZHAO Chong-zhi LIU Gui-jun SUN Dong-tao |
| Affiliation: | PAN De-sheng1,WANG Cheng-lin1,DIAO Hong-yu1,QI Jian-fei1,ZHAO Chong-zhi1,LIU Gui-jun2,SUN Dong-tao31. Department of Neurosurgery,The Second Affiliated Hospital,China Medical University,Shenyang 110004,China, 2. Department of Neurosurgery,Central Hospital,Huludao City, 3. Department of Neurosurgery,The Second Affiliated Hospital,Shenyang Medical College) |
| Abstract: | Objective: Our aim was to detect the expression of interleukin-6 (IL-6) mRNA in human gliomas. Methods:RT-PCR semi-quantity method was used to determine the expression rate of IL-6 mRNA in 34 cases of gliomas and 8 normal brain tissues. Results:The expression rates of IL-6 mRNA in cases of gliomas and normal brain tissues were 79.4% and 12.5% respectively. The difference was statistically significant. The high expression rate of IL-6 mRNA correlates with the pathological grades of gliomas. Conclusion:It suggests that IL-6 may play an important role in gliomas. |
| Keywords: | interleukin-6 mRNA gliomas |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |
