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Endocare型氩氦冷刀冻结与复温性能的实验研究
引用本文:于天骅,王洪武,周一欣,刘静,冯华松,陆海英.Endocare型氩氦冷刀冻结与复温性能的实验研究[J].航天医学与医学工程,2003,16(1):60-62.
作者姓名:于天骅  王洪武  周一欣  刘静  冯华松  陆海英
作者单位:1. 中国科学院理化技术研究所低温中心,北京,100080
2. 海军总医院氩氦刀肿瘤治疗中心,北京,100037
基金项目:中国科学院“百人计划”资助项目
摘    要:目的:对Endocare型氩氦冷刀的实际工作性能进行测试,考察其优缺点,为肿瘤冷冻治疗提供参考。方法:将氩氦刀置于空气、水及哆子组织中进行冷冻并复温,监测刀杆外壁和内部测温点的温度变化;基于实验结果评价氩氦刀的工作性能以及工质气体的消耗情况;结果:氩氦刀冷冻时,刀头在很短的时间内降至极低温度,并保持稳定。冰球在冷冻初期增长很快,此后其增长速率明显下降。当工质由氩切换为氦后,刀头温度迅速上升,冰球随即熔化;工质气体的消耗速率随着实验进行不断降低。结论:证实氩氦刀确有良好的快速冷冻和复温性能,但同时也存在问题和不足。

关 键 词:实验研究  冷冻刀  活体生物组织  冻结  复温  气体消耗速率  冷冻外科
文章编号:1002-0837(2003)01-0060-04
修稿时间:2002年2月10日

Measurement and Analysis of Operation Performance of the "Endocare" Cryoprobe System
YU Tian hua,WANG Hong wu,ZHOU Yi xin,LIU Jing,FENG Hua song,LU Hai yingCryogenics Laboratory,Technical Institute of Physics and Chemistry,Chinese Academy of Sciences,Beijing ,China.Measurement and Analysis of Operation Performance of the "Endocare" Cryoprobe System[J].Space Medicine & Medical Engineering,2003,16(1):60-62.
Authors:YU Tian hua  WANG Hong wu  ZHOU Yi xin  LIU Jing  FENG Hua song  LU Hai yingCryogenics Laboratory  Technical Institute of Physics and Chemistry  Chinese Academy of Sciences  Beijing  China
Affiliation:YU Tian hua,WANG Hong wu,ZHOU Yi xin,LIU Jing,FENG Hua song,LU Hai yingCryogenics Laboratory,Technical Institute of Physics and Chemistry,Chinese Academy of Sciences,Beijing 100080,China
Abstract:Objective To test the working performance of the Endocare Cryoprobe System and to evaluate its advantages and shortcomings for clinical application in targeted tumor treatment. Method The cryoprobe was placed into air, distilled water, and rabbit tissues to observe its freezing and rewarming behaviors. The transient temperatures at the exterior wall and interior of the cryoprobe were monitored. The output performance of the cryoprobe and the consumption rate of the working gases were evaluated basing on the measurements. Result The temperature at the cryoprobe tip inserted into tissues decreased quickly to its lowest value and kept relatively stable during freezing. The iceball grew quickly at the initial period of freezing and then slowed down. The temperature at the cryoprobe tip increased quickly when the working gas was shifted to He. In several minutes, the iceball became thawed. The consumption rate of Ar and He gases decreased with the operation of the cryoprobe. Conclusion The Endocare Cryoprobe System had excellent performances in quick freezing and rewarming. However, it also has certain disadvantages, which were briefly discussed in this paper.
Keywords:cryoprobe  in  vivo tissues  freezing  rewarming  gas consumption rate  cryosurgery
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