| 高效液相色谱法测定鼻康喷雾剂中木兰脂素的含量 |
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| 引用本文： | 李亚山,王立兴.高效液相色谱法测定鼻康喷雾剂中木兰脂素的含量[J].海峡药学,2011,23(12):59-60. |
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| 作者姓名： | 李亚山 王立兴 |
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| 作者单位： | 1. 福建医科大学附属口腔医院 福州 350002
2. 福州长富星新药开发有限公司 福州 350002 |
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| 摘 要： | 目的建立高效液相色谱法测定鼻康喷雾剂中木兰脂素的含量。方法选用Allsphere-C18色谱柱（250mm×4.6mm,5μm）,以乙腈-3.3%四氢呋喃溶液（34：66）为流动相,检测波长为278nm,柱温为30℃,流速为1.2mL.min-1。结果木兰脂素在0.0936～1.872μg范围内线性关系良好,r=0.9999。平均回收率为98.6%,RSD为1.26%。结论该方法准确可靠、精密度高、重现性好,可用于鼻康喷雾剂中木兰脂素的含量测定。
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| 关 键 词： | 鼻康喷雾剂 木兰脂素 高效液相色谱法 |
Determination of Magnolin in Bikang Spray by HPLC |
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| LI Ya-shan
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WANG Li-xing.Determination of Magnolin in Bikang Spray by HPLC[J].Strait Pharmaceutical Journal,2011,23(12):59-60. |
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| Authors: | LI Ya-shan WANG Li-xing |
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| Affiliation: | 1.The stomato logical hospital affitaded of Fujian medical univertity Fuzhou 350002;2.Fuhou changfuxing new drug develop-ment Co.Ltd.Fuzhou 350002,China) |
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| Abstract: | OBJECTIVE To establish a HPLC method for determination of Magnolin in Bikang spray.METHODS Allspher-C18 column(250mm×4.6mm 5μm) was used at 30℃,the mobile phase composition was acetonitril-3.3% tetrahydrofuran(34∶66),the detection wavelength was 278 nm,the flow rate was 1.2mL·min-1.RESUTLS Magnolin showed a good linear relationship in the range of 0.0936～1.872μg,r=0.9999.The average recovery was 98.6%,RSD was 1.26%.CONCLUSION The established method is accurate、reliable、high precision、good repeatability and can be used for the determination of Magnolin in Bikang spray. |
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| Keywords: | Bikang spray Magnolin HPLC |
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