148例药品不良反应报告分析

目的：了解药品不良反应的发生情况及产生原因，为临床合理用药提供参考。方法：对奉贤区中医医院2011年1月-2013年12月收集到的148例药品不良反应报告进行回顾性分析。结果：抗感染药物的不良反应发生率最高，占总数的62.8%（93例）；其次为中成药，占总数的21.6%（32例）。静脉给药引发的药品不良反应占95.9%（142例），药品不良反应的临床表现以皮疹、瘙痒等皮肤及其附件损害最为常见。结论：应充分重视药品的不良反应，加强对药品不良反应的监测和管理力度，指导临床合理使用抗感染药及中药注射剂，避免或减少药品不良反应的重复发生。

Report on the analysis of 148 cases of adverse drug reactions

Objective：To understand the adverse drug reactions （ADR） occurred and their reasons, and provide a reference for clinical rational drug use. Methods：The data of 148 cases of ADR occurred from Jan. 2011 to Dec. 2013 were retrospectively analyzed. Results：Incidence of ADR of anti-infective drugs was the highest, accounting for 62.8%（93 cases）, followed by Chinese medicine 21.6%（32 cases）. ADR caused by intravenous administration accounted for 95.9%（142 cases）. Skin rashes and itching and other skin damage are the most common in clinical manifestations of ADR. Conclusion：Sufifcient attention should be paid to ADR, and the monitoring and management of ADR should be strengthened so as to guide the clinical rational use of anti-infective drugs and traditional Chinese medicine injection and to avoid or reduce the recurrence of ADR.