| THE EFFECT OF ACTIVE COMPONENTS OF LYCIUM BARBARUM AND GARLIC（LB－GO）ON THE SYNTHESIS OF DNA AND ULTRASTRUCTURE OF U_（14） CERV |
| |
| 引用本文： | 胡庆和,高天顺,赵承军,张焱,谢锦玉,沈联慈,刘铭福.THE EFFECT OF ACTIVE COMPONENTS OF LYCIUM BARBARUM AND GARLIC（LB－GO）ON THE SYNTHESIS OF DNA AND ULTRASTRUCTURE OF U_（14） CERV[J].中国癌症研究,1994,6(4):266-273. |
| |
| 作者姓名： | 胡庆和 高天顺 赵承军 张焱 谢锦玉 沈联慈 刘铭福 |
| |
| 作者单位： | Hu Qinghe; Gao Tianshun ; Zhao Chengjun;Zhang Yan;(Ningxia Medical College，Yinchuan，750004)Xie Jinyu;Sheng Lianci;Liu mingfu(Institute of Basic Theory Research，China Academy of Traditional Chinese Medicine，Beijing，100700) |
| |
| 摘 要： | ＴＨＥＥＦＦＥＣＴＯＦＡＣＴＩＶＥＣＯＭＰＯＮＥＮＴＳＯＦＬＹＣＩＵＭＢＡＲＢＡＲＵＭＡＮＤＧＡＲＬＩＣ（ＬＢ－ＧＯ）ＯＮＴＨＥＳＹＮＴＨＥＳＩＳＯＦＤＮＡＡＮＤＵＬＴＲＡＳＴＲＵＣＴＵＲＥＯＦＵ_（１４）ＣＥＲＶＩＸＣＡＮＣＥＲＣＥＬＬＳＩＮＭＩＣ?..
|
The effect of active components of Lycium barbarum and garlic (LB-GO) on the synthesis of dna and ultrastructure of u14 cervix cancer cells in mice |
| |
| Qinghe Hu,Tianshun Gao,Chengjun Zhao,Yan Zhang,Jinyu Xie,Lianci Sheng,mingfu Liu.The effect of active components of Lycium barbarum and garlic (LB-GO) on the synthesis of dna and ultrastructure of u14 cervix cancer cells in mice[J].Chinese Journal of Cancer Research,1994,6(4):266-273. |
| |
| Authors: | Qinghe Hu Tianshun Gao Chengjun Zhao Yan Zhang Jinyu Xie Lianci Sheng mingfu Liu |
| |
| Affiliation: | 1. Ningxia Medical College, 750004, Yinchuan
2. Institute of Basic Theory Research, China Academy of Traditional Chinese Medicine, 100700, Beijing
|
| |
| Abstract: | Mice, inoculated with U_(14) ascitic type cervix cancer cells, were administered with effective components of Lycium barbarum (LB) and garlic (GO).On the 4th day after i.p.administration, general condition of the animals were found improved.Examination of ascitic fluid revealed damage of the cancer cells, blanching of fluorescence staining of DNA and RNA, and the cancer cells besieged by large numbers of macrophages and leucocytes. Flow cell metric (FCM) analysis found: accumulation of cells of G_1 stage. Ultrastructure study disclosed: swelling of mitochondria in cytoplasm and damage of mitochondrial crests even with cavity formation, enlargement and degranulation of rough ER. It seemed the effect of LBGO was affirmable. It was postulated that macrophages,being activated by LB, came in close contact with the cancer cells giving rise to carcinolysis. In addition to the direct but transient killing effect of GO, the anti-cancer results could be greatly enhanced. |
| |
| Keywords: | Lycium barbarum Garlic U_(14) Cervix cancer cell DNA synthesis Ultrastructure |
| 本文献已被 CNKI SpringerLink 等数据库收录！ |
